HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is a HTR2A antagonist, with an IC50 of 42.79 nM. HTR2A antagonist 1 induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells via the activation of p53/p21/caspase 3 signaling. HTR2A antagonist 1 has good liver microsomal stability. HTR2A antagonist 1 can be used for the research of colorectal cancer.
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- Fòrmula: C35H43Cl2F2N5O4
- Peso molecular:706.65
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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Peso molecular 706.65
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Fòrmula C35H43Cl2F2N5O4
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SMILES
O=C(NCC1=CC=C(OCC(O)CN2CCC(C3=NOC4=CC(F)=CC=C34)CC2)C=C1)N(CC5=CC=C(F)C=C5)C6CCNCC6.Cl.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)