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Cat. No.: HY-129671

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Polypodine B

(Synonyms: 5β-Hydroxyecdysterone)

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Polypodine B is a natural ecdysone ester isolated from the bark of Dacrydium intermedium. Polypodine B significantly inhibits the activity of Acanthamoeba castellani. Polypodine B has moderate antifungal activity. Polypodine B can be used for research on parasitic diseases and fungal infections.

For research use only. We do not sell to patients.

Purity: 98.60%
CAS No.: 18069-14-2
Formula: C₂₇H₄₄O₈
Molecular Weight:496.63

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Polypodine B Chemical Structure

CAS No.: 18069-14-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Parasite Isoforms :

In Vitro

Polypodine B (0.05-0.5 mg/mL, 1-3 days) has an inhibition rate of about 96% on the growth of Acanthamoeba castellani (IC₅₀ = 0.07 mg/mL) on the third day at 0.5 mg/mL^[2].
Polypodine B (0.5-1 mg/mL, 5-15 min) does not show significant toxicity to Aliivibrio fischeri at 0.5 mg/mL^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 18069-14-2
Appearance Solid
Molecular Weight 496.63
Formula C₂₇H₄₄O₈
Color White to off-white
SMILES

O[C@]([C@@]1(CC2)C)(CC[C@]1([H])[C@@](C)(O)[C@H](O)CCC(C)(O)C)C([C@@]2([H])[C@]([C@]3(C[C@H]4O)O)(C[C@@H]4O)C)=CC3=O
Synonyms

5β-Hydroxyecdysterone
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (280 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. G Russell, et al. Insect Moulting Hormones: The Phytoecdysones of Dacrydium Intermedium.

[2]. Maliński MP, et al. Two Ecdysteroids Isolated from Micropropagated Lychnis flos-cuculi and the Biological Activity of Plant Material. Molecules. 2021 Feb 9;26(4):904. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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Polypodine B

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Polypodine B Related Classifications

HY-129671 Related Classifications