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  3. Isolimonexic acid

Isolimonexic acid 

Cat. No.: HY-N8405
Handling Instructions

Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties.

For research use only. We do not sell to patients.

Isolimonexic acid Chemical Structure

Isolimonexic acid Chemical Structure

CAS No. : 73904-93-5

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Description

Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties[1].

IC50 & Target

IC50: 25.60 μM (aromatase)[1]

In Vitro

Isolimonexic acid (200 μM; 72 hours) exhibits cytotoxicity on MCF-7 cells and shows no cytotoxicity against the MDA-MB-231 cell lines[1].
Isolimonexic acid (50 μg/ml; 48, 96 and 144 hours) exhibits cell growth inhibition of Panc-28 cells in a time-dependent manner.And it percent inhibition comparison to control cells are 21%, 68%, and 90.58% at 48, 72, and 144 h, respectively[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

502.51

Formula

C₂₆H₃₀O₁₀

CAS No.

73904-93-5

SMILES

C[[email protected]]12[[email protected]]34[[email protected]](C(O[[email protected]](C5=CC(OC5=O)O)([H])[[email protected]@]4(CC[[email protected]]1([H])[[email protected]]67[[email protected]@](C(C)(O[[email protected]@]6([H])CC(OC7)=O)C)([H])CC2=O)C)=O)([H])O3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Isolimonexic acidAromataseMCF-7ER-positivebreast canceranti-aromataselimonoidPancreaticInhibitorinhibitorinhibit

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Isolimonexic acid
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