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Cat. No.: HY-N8337

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IT-143B

IT-143B is an antibiotic, that exhibits antibacterial activity against Micrococcus luteus with MIC of 6.25μg/mL. IT-143B inhibits growth of cancer cell KB with an IC₅₀ of 1.1 ng/mL.

For research use only. We do not sell to patients.

CAS No.: 183485-34-9
Formula: C₂₈H₄₁NO₄
Molecular Weight:455.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

IT-143B Chemical Structure

CAS No.: 183485-34-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

IT-143B is an antibiotic, that exhibits antibacterial activity against Micrococcus luteus with MIC of 6.25μg/mL. IT-143B inhibits growth of cancer cell KB with an IC₅₀ of 1.1 ng/mL^[1].

All Antibiotic Isoforms :

Chemical Information

CAS No. 183485-34-9
Molecular Weight 455.63
Formula C₂₈H₄₁NO₄
SMILES

COC(C(O)=C1C)=C(N=C1C/C=C(C)/C/C=C/C(C)=C/[C@@H](C)[C@@H](O)/C(C)=C/C(C)=C/C)OC
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Urakawa A, et al., IT-143-A and B, novel piericidin-group antibiotics produced by Streptomyces sp. J Antibiot (Tokyo). 1996 Oct;49(10):1052-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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IT-143B

All Antibiotic Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

IT-143B Related Classifications

HY-N8337 Related Classifications