A63162
A63162 is a specific 5-lipoxygenase (5-LOX) inhibitor. A63162 inhibits mitogen (PHA)-induced horse mononuclear cell (BMC) proliferation and inhibits Calcimycin (HY-N6687)-induced leukotriene LTB4 synthesis at the same concentration. A63162 can be used in the study of chronic obstructive pulmonary disease, arthritis and inflammatory bowel disease.
For research use only. We do not sell to patients.
- CAS No.: 111525-11-2
- Formula: C17H19NO3
- Molecular Weight:285.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Leukotriene Receptor Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
0.37 μM
Compound: 4b
|
In vitro inhibition of 5-lipoxygenase in RBL-1 cells
In vitro inhibition of 5-lipoxygenase in RBL-1 cells
|
[PMID: 3336029] |
Chemical Information
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CAS No. 111525-11-2
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Molecular Weight 285.34
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Formula C17H19NO3
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SMILES
CC(N(C(C)C1=CC=C(C=C1)OCC2=CC=CC=C2)O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)