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スルファサラジン

(別名: Sulfasalazine)
84 Cited Publications
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Based on 84 publication(s) in Google Scholar

Sulfasalazine (NSC 667219) is an anti-rheumatic agent for the research of rheumatoid arthritis and ulcerative colitis. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 99.57%
  • CAS 番号: 599-79-1
  • 分子式: C18H14N4O5S
  • 分子量:398.39
  • 保管条件:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • Sulfasalazine Chemical Structure
    Sulfasalazine 構造式
  • Experimental Validation Results for Sulfasalazine
  • Experimental Validation Results for Sulfasalazine
  • Experimental Validation Results for Sulfasalazine
  • Experimental Validation Results for Sulfasalazine
  • Experimental Validation Results for Sulfasalazine
CAS 番号: 599-79-1
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最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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MedChemExpress（MCE）の使用を引用している文献 Sulfasalazine

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2D/3D Cell Culture and DifferentiationIn Vivo Efficacy StudyHistological Imaging/StainingWB
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  • In Vivo Efficacy Study
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  • Sulfasalazine Chemical Structure
    Sulfasalazine Chemical Structure
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    Sulfasalazine purchased from MedChemExpress. Usage Cited in: Cancer Commun (Lond). 2025 Dec 25.

    Customer Validation
     Sulfasalazine (SSA, 0.1–100 mM, 24 h) inhibited cell growth in parental HCCLM3 cells and the indicated clones with reconstituted expression of the WTAP S176A (left) or knock-in expression of GLS Mut (right).

  • 1/16

    Sulfasalazine purchased from MedChemExpress. Usage Cited in: Cancer Commun (Lond). 2025 Dec 25.

    Customer Validation
     Sulfasalazine (SAS, 100 mg/kg, i.p., 30 days) inhibited tumor growth in athymic nude mice bearing HCCLM3 cells with wildtype or WTAP S176A mutant.

  • 1/16

    Sulfasalazine purchased from MedChemExpress. Usage Cited in: Cancer Commun (Lond). 2025 Dec 25.

    Customer Validation
     Sulfasalazine (SAS, 100 mg/kg, i.p., 30 days) decreased GAC expression and increased 4-HE expression in athymic nude mice bearing either wildtype HCCLM3 cells or cells expressing the WTAP S176A mutant.

  • 1/16

    Sulfasalazine purchased from MedChemExpress. Usage Cited in: Mol Ther. 2021 Jul 7;29(7):2321-2334. [Abstract]

    Customer Validation
     PD-L1 expression is significantly increased after Sulfasalazine (SAS) treatment at both the protein and mRNA levels.

  • 1/16

    Sulfasalazine purchased from MedChemExpress. Usage Cited in: Cell Res. 2018 Dec;28(12):1171-1185. [Abstract]

    Customer Validation
     Melanoma A375 cells are treated with SSZ (Sulfasalazine, 125 μM) with or without FeSO4 (100 μM) for 6 h to detect the ROS level or 24 h to assess the pyroptotic features (including morphology, GSDME cleavage, and LDH release), unless specifically defined.

  • Sulfasalazine