A-39183A
A-39183A is an antibiotic that shows significant cytotoxicity to HeLa cells, with an IC50 value of 1.8 μM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 79426-51-0
- 分子式: C34H30O10
- 分子量:598.60
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Antibiotic アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
>10 μM
Compound: 2; A-39183A
|
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by SRB assay
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by SRB assay
|
[PMID: 32880456] |
| HeLa | IC50 |
1.8 μM
Compound: 2; A-39183A
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by SRB assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by SRB assay
|
[PMID: 32880456] |
| HL-60 | IC50 |
>10 μM
Compound: 2; A-39183A
|
Cytotoxicity against human HL-60 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Cytotoxicity against human HL-60 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 32880456] |
| K562 | IC50 |
5.1 μM
Compound: 2; A-39183A
|
Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 32880456] |
化学情報
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CAS 番号 79426-51-0
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分子量 598.60
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分子式 C34H30O10
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SMILES
O=C1C[C@](C)(O)[C@@H](C(C)=O)C2=C1C(O)=C3C(O)=CC=CC3=C2C4=C5C=CC=C(O)C5=C(O)C6=C4[C@H](C(C)=O)[C@@](C)(O)CC6=O
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Structure Classification
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Initial Source
Streptomyces fumigatiscleroticus
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)