Anticancer agent 298
Anticancer agent 298 is a bi-nuclear Cu(II)-hydrazone complexe. Anticancer agent 298 can bind to the CDK-2 active site (PDB ID: 3IG7) via hydrogen bonds with key amino acid residues. Anticancer agent 298 exerts cytotoxic effects against hepatocellular carcinoma cells, and has lower cytotoxicity against normal human embryonic kidney cells. Anticancer agent 298 can be used for the research of hepatocellular carcinoma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C36H54Br2Cu2N6O12
- 分子量:1049.75
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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CDK2 |
Anticancer agent 298 (Compound 2) potently inhibits hepatocellular carcinoma (HepG-2) cells with an IC50 of 12.27 μM and has an IC50 of 90.16 μM against normal human embryonic kidney (HEK-2) cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 1049.75
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分子式 C36H54Br2Cu2N6O12
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SMILES
CC(C1=C(O[Cu]2([OH]CC)([OH]CC)([OH]CC)Br)C=C(O[Cu]3([OH]CC)([OH]CC)([OH]CC)Br)C(C(C)=[N]3/N=C/C4=CC=CC([N+]([O-])=O)=C4)=C1)=[N]2/N=C/C5=CC([N+]([O-])=O)=CC=C5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Anticancer agent 298 関連分類
HY-181116 関連分類
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