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製品番号: HY-123886

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Aranciamycin

Aranciamycin (Compound 1) is an anthracycline antibiotic with collagenase inhibitory activity (IC₅₀3.7*10_-7M). Aranciamycin can be used to inhibit DNA synthesis in tumor cells .

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CAS 番号: 72389-06-1
分子式: C₂₇H₂₈O₁₂
分子量:544.50

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Aranciamycin 構造式

CAS 番号: 72389-06-1

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Aranciamycin (Compound 1) is an anthracycline antibiotic with collagenase inhibitory activity (IC₅₀3.7*10_-7M). Aranciamycin can be used to inhibit DNA synthesis in tumor cells ^[1].

Antibiotic アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	2.7 μM Compound: 7	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay	[PMID: 38412432]
HeLa	IC₅₀	2.7 μM Compound: 3	Cytotoxicity against human HeLa cells after 48 hrs by WST8 assay Cytotoxicity against human HeLa cells after 48 hrs by WST8 assay	[PMID: 20192240]
HepG2	IC₅₀	18 μM Compound: 4	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25789410]
HL-60	IC₅₀	4.1 μM Compound: 3	Cytotoxicity against human HL60 cells after 48 hrs by WST8 assay Cytotoxicity against human HL60 cells after 48 hrs by WST8 assay	[PMID: 20192240]
KB 3-1	IC₅₀	>30 μM Compound: 4	Cytotoxicity against human KB-3-1 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human KB-3-1 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25789410]
NCI-H460	IC₅₀	>30 μM Compound: 4	Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25789410]
PC-3	IC₅₀	1.1 μM Compound: 7	Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay	[PMID: 38412432]
SW-620	IC₅₀	>30 μM Compound: 4	Cytotoxicity against human SW620 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human SW620 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25789410]

化学情報

CAS 番号 72389-06-1
分子量 544.50
分子式 C₂₇H₂₈O₁₂
SMILES

O=C1[C@@](C)(O)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H]([C@H]([C@H](C)O2)O)O)OC)C(C(O)=C3C(C4=C5C=CC=C4O)=O)=C1C=C3C5=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (271 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Bols M, et al. Inhibition of collagenase by aranciamycin and aranciamycin derivatives. J Med Chem. 1992 Jul 24;35(15):2768-71. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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