BRD4-IN-5
BRD4-IN-5 (example 51) is a BRD4 inhibitor. The Ki values of the two BRD4 domains BDI_K57-E168 and BDII_E352-M457 are 9.7 nM and 16.1 nM, respectively. BRD4-IN-5 can be used in cancer research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1445993-41-8
- 分子式: C25H21F2N3O4
- 分子量:465.45
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
BDI_K57-E168 9.7 nM (Ki) |
BDII_E352-M457 16.1 nM (Ki) |
BRD4-IN-5 (example 51) has half-lives of 6 minutes in human liver microsomes, 63 minutes in mouse liver microsomes, and more than 120 minutes in rat liver microsomes, respectively[1]. BRD4-IN-5 (3 days) inhibits cell proliferation against the breast cancer cell line MX-1, with an EC50 of 0.101 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 1445993-41-8
-
分子量 465.45
-
分子式 C25H21F2N3O4
-
SMILES
CN1C=C(C2=C(OC3=C(F)C=C(F)C=C3)C=CC(C(NC4CCOC4)=O)=C2)C5=C(NC=C5)C1=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
BRD4-IN-5 関連分類
HY-160662 関連分類
Powered by Bioz