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製品番号: HY-N19724

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Buddledin A

Buddledin A is a 5-LOX inhibitor (IC₅₀ = 50.4 μM) and a COX inhibitor (IC₅₀ = 13.7 μM). Buddedin A inhibits arachidonic acid metabolism via the 5-LOX and COX pathways, suppresses fungal growth, and exerts toxic effects on fish. Buddedin A may play an ecological role in protecting plant roots and stem barks from fungal infection. Buddedin A can be used in studies related to fungal infections.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 62346-20-7
分子式: C₁₇H₂₄O₃
分子量:276.37

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Buddledin A 構造式

CAS 番号: 62346-20-7

容量

価格（税別）

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target^[1]

5-LOX

Lipoxygenase アイソフォーム固有の製品をすべて表示 :

COX アイソフォーム固有の製品をすべて表示 :

体外実験

Buddledin A potently inhibits COX activity in activated rat peritoneal leukocytes, with an IC₅₀ value of 13.7 μM^[1].
Buddledin A inhibits the activity of 5-LOX in activated rat peritoneal leukocytes, with an IC₅₀ of 50.4 μM^[1].
Buddledin A (12.5 mg/mL) inhibits the growth of Epidermophyton floccosum, Trichophyton interdigitale, Fusarium graminearum and Sordaria fimicola, with an MIC of 12.5 mg/mL^[2].
Buddledin A (10 mg/m, 25°C, after 5 to 7 days) inhibits the growth of Fusarium solani^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 62346-20-7
分子量 276.37
分子式 C₁₇H₂₄O₃
SMILES

O=C(/C(C)=C/CC1)[C@H](OC(C)=O)[C@@]2([H])C(C)(C)C[C@]2([H])C1=C
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Liao YH, et al. Novel and known constituents from Buddleja species and their activity against leukocyte eicosanoid generation. J Nat Prod. 1999;62(9):1241-1245. [Content Brief]

[2]. Houghton PJ, et al. Terpenoids in Buddleja: relevance to chemosystematics, chemical ecology and biological activity. Phytochemistry. 2003;64(2):385-393. [Content Brief]

[3]. Takashi Yoshida, et al. Buddledin A, B and C, piscicidal sesquiterpenes from Buddleja davidi[CITATION]Franch. Tetrahedron Letters No. 41, pp 3717-3720, 1976. Pergamon Press.
Printed in Great Britain.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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濃度濃度

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希釈計算機

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体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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生物活性
- 製品説明
- IC₅₀ & Target
- 体外実験
化学情報
純度とドキュメンテーション
参考文献

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Buddledin A

Lipoxygenase アイソフォーム固有の製品をすべて表示

COX アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Buddledin A 関連分類

HY-N19724 関連分類