CDK2-IN-40
Based on 1 Customer Validation
CDK2-IN-40 is a CDK2 (Cyclin dependent kinase 2) inhibitor, extracted from patent WO 2024/254245 A1 (Example 1). CDK2-IN-40 inhibits CDK2/Cyclin E1 with an IC50 of ≤ 10 nM.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.80%
- CAS 番号: 3065079-44-6
- 分子式: C16H21N7O2
- 分子量:343.38
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
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CDK2/cyclinE 10 nM (IC50) |
化学情報
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CAS 番号 3065079-44-6
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性状 Solid
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分子量 343.38
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分子式 C16H21N7O2
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Color White to off-white
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SMILES
CC(C)OC1=C(N=CN2C1=NC(NC3CCOCC3)=N2)C4=CNN=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (364.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9122 mL | 14.5611 mL | 29.1223 mL | 72.8056 mL |
| 5 mM | 0.5824 mL | 2.9122 mL | 5.8245 mL | 14.5611 mL | |
| 10 mM | 0.2912 mL | 1.4561 mL | 2.9122 mL | 7.2806 mL | |
| 15 mM | 0.1941 mL | 0.9707 mL | 1.9415 mL | 4.8537 mL | |
| 20 mM | 0.1456 mL | 0.7281 mL | 1.4561 mL | 3.6403 mL | |
| 25 mM | 0.1165 mL | 0.5824 mL | 1.1649 mL | 2.9122 mL | |
| 30 mM | 0.0971 mL | 0.4854 mL | 0.9707 mL | 2.4269 mL | |
| 40 mM | 0.0728 mL | 0.3640 mL | 0.7281 mL | 1.8201 mL | |
| 50 mM | 0.0582 mL | 0.2912 mL | 0.5824 mL | 1.4561 mL | |
| 60 mM | 0.0485 mL | 0.2427 mL | 0.4854 mL | 1.2134 mL | |
| 80 mM | 0.0364 mL | 0.1820 mL | 0.3640 mL | 0.9101 mL | |
| 100 mM | 0.0291 mL | 0.1456 mL | 0.2912 mL | 0.7281 mL |