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United States

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製品番号: HY-184418

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CDK4-IN-6

CDK4-IN-6 is a CDK4 inhibitor with an IC₅₀ of 0.0011 μM. CDK4-IN-6 can be used for the research of breast cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 3120500-44-6
分子式: C₂₀H₂₉FN₆O₃S
分子量:452.55

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK4-IN-6 構造式

CAS 番号: 3120500-44-6

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

CDK4-IN-6 is a CDK4 inhibitor with an IC₅₀ of 0.0011 μM. CDK4-IN-6 can be used for the research of breast cancer^[1].

IC₅₀ & Target

^[1]

CDK4

0.0011 μM (IC₅₀)

CDK アイソフォーム固有の製品をすべて表示 :

体外実験

CDK4-IN-6 (compound 95) inhibits human CDK4 with an IC₅₀ of 0.0011 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

化学情報

CAS 番号 3120500-44-6
分子量 452.55
分子式 C₂₀H₂₉FN₆O₃S
SMILES

O[C@H](CN(S(=O)(C)=O)CC1)[C@@H]1NC2=NC=C3C(N([C@@H]4CCNC[C@@H]4F)C(C5CC5)=C3)=N2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

プロトコル

All Cell Biology Animals and Diseases

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Sabnis R W. Novel Compounds as CDK4 Inhibitors for Treating Breast Cancer. ACS Medicinal Chemistry Letters. 2026.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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濃度濃度

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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