CDK9-IN-48
CDK9-IN-48 is a CDK9 inhibitor with an IC50 of 1.37 nM. CDK9-IN-48 inhibits the proliferation of various cancer cells. CDK9-IN-48 can be used in the research of cancers such as acute myeloid leukemia and prostate cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2987897-20-9
- 分子式: C23H24FN5O3S
- 分子量:469.53
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
CDK9 1.37 nM (IC50) |
CDK9-IN-48 (Example 18) (0.00000256-1 μM, 3 days) potently inhibits the proliferation of MOLM-13 acute myeloid leukemia cells, LNCaP prostate cancer cells, and MV-4-11 acute myeloid leukemia cells, with IC50 values of 0.645, 2.34, and 2.24 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:MOLM-13, LNCaP, MV-4-11 cell
-
Concentration:0.00000256-1μM, starting with 1 μM, a 5-fold serial dilution was performed to obtain 9 concentrations
-
Incubation Time:2 days (post-compound addition, 37°C, 5% CO2)
-
Result:Potently inhibited MOLM-13 cell proliferation with an IC50 of 0.645 nM.
Inhibited LNCaP cell proliferation with an IC50 of 2.34 nM.
Inhibited MV-4-11 cell proliferation with an IC50 of 2.24 nM.
化学情報
-
CAS 番号 2987897-20-9
-
分子量 469.53
-
分子式 C23H24FN5O3S
-
SMILES
CN1C(C(C)(O)C)=C2C=C(C3=C(F)C=NC(NC4=CC(CS(C)(=O)=O)=CC=N4)=C3)C=CC2=N1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CDK9-IN-48 関連分類
HY-185339 関連分類
Powered by Bioz