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製品番号: HY-163804

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Cyprocide-B

Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide.

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CAS 番号: 49809-25-8
分子式: C₁₀H₉ClN₂OS
分子量:240.71

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Cyprocide-B 構造式

CAS 番号: 49809-25-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide^[1].

Cytochrome P450 アイソフォーム固有の製品をすべて表示 :

Parasite アイソフォーム固有の製品をすべて表示 :

体外実験

Cyprocide-B (50 µM, 3 days) is a selective nematicide with broad-spectrum activity in plant-parasitic nematodes (PPNs), and is safer for zebrafish than Tioxazafen (HY-136240)^[1].
Cyprocide-B (25 μM, 24 h) is bioactivated by CYP-35D1 to produce a reactive electrophile in C. elegans^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

Human cells, fungi, plant beneficial rhizobacteria
Concentration:

50 µM
Incubation Time:

3 days
Result:

Was relatively inactive against non-nematode phyla at the same concentration of killing nematodes in vitro.

体内実験

Cyprocide-B (60 μM, 24 h) has potential utility in preventing root infestation by M. incognita in a soil environment^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 49809-25-8
分子量 240.71
分子式 C₁₀H₉ClN₂OS
SMILES

CCSC1=NN=C(C2=CC=C(Cl)C=C2)O1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (266 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Knox J, et al. Cyprocide selectively kills nematodes via cytochrome P450 bioactivation[J]. Nat Commun. 2024 Jul 2;15(1):5529. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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生物活性
- 製品説明
- 体外実験
- 体内実験
化学情報
純度とドキュメンテーション
参考文献

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Cyprocide-B

Cytochrome P450 アイソフォーム固有の製品をすべて表示

Parasite アイソフォーム固有の製品をすべて表示