Desotamide
Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 194660-14-5
- 分子式: C35H52N8O7
- 分子量:696.84
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
|
[PMID: 25072108] |
| MCF7 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
|
[PMID: 25072108] |
| NCI-H460 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human NCI-H460 after 72 hrs by SRB assay
Cytotoxicity against human NCI-H460 after 72 hrs by SRB assay
|
[PMID: 25072108] |
| SF-268 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human SF268 cells after 72 hrs by SRB assay
Cytotoxicity against human SF268 cells after 72 hrs by SRB assay
|
[PMID: 25072108] |
化学情報
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CAS 番号 194660-14-5
-
分子量 696.84
-
分子式 C35H52N8O7
-
別名
Desotamide A
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配列
cyclo(Asn-Gly-Trp-Leu-Leu-Ile)
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シーケンスの短縮
cyclo(NGWLLI)
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)