Esculentoside B
Based on 1 Customer Validation
Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.88%
- CAS 番号: 60820-94-2
- 分子式: C36H56O11
- 分子量:664.82
-
保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
74.7 μM
Compound: 9
|
Cytotoxicity against human HepG2 cells
Cytotoxicity against human HepG2 cells
|
[PMID: 18177012] |
| WI-38 | IC50 |
36.2 μM
Compound: 9
|
Cytotoxicity against human WI38 cells
Cytotoxicity against human WI38 cells
|
[PMID: 18177012] |
| WI-38 VA13 | IC50 |
68.9 μM
Compound: 9
|
Cytotoxicity against human VA13 cells
Cytotoxicity against human VA13 cells
|
[PMID: 18177012] |
化学情報
-
CAS 番号 60820-94-2
-
性状 Solid
-
分子量 664.82
-
分子式 C36H56O11
-
Color White to off-white
-
SMILES
C[C@@]12C([C@@]3([H])[C@](C(O)=O)(CC[C@@](C(OC)=O)(C)C3)CC2)=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(C[C@H](O)[C@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O)CO6)O)O)[C@@]5(C)CO)C)C
-
別名
Phytolaccoside B
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
-
データシート (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Abekura F, et al. Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells. Int Immunopharmacol. 2019;68:156-163. [Content Brief]
[2]. Ren S, et al. Metabolic exploration of the developmental abnormalities and neurotoxicity of Esculentoside B, the main toxic factor in Phytolaccae radix. Food Chem Toxicol. 2023;176:113777. [Content Brief]
[3]. Escalante A, et al. Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. J Nat Prod. 2008;71(10):1720-1725. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Esculentoside B 関連分類
HY-N6032 関連分類
Powered by Bioz