HLDA-221
Based on 1 Customer Validation
HLDA-221 is a non-covalent regulated induced proximity targeting chimeras (RIPTAC). The binding of HLDA-221 to BRD4-BD1 is significantly increased after pre-incubation with FKBP. HLDA-221 can be used in cancer research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.24%
- CAS 番号: 3077339-82-0
- 分子式: C64H78ClN7O13S
- 分子量:1220.86
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
生物活性
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BRD4 (BD1) |
化学情報
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CAS 番号 3077339-82-0
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性状 Solid
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分子量 1220.86
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分子式 C64H78ClN7O13S
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Color White to off-white
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SMILES
CC(C(C(C(C=C1)=CC=C1Cl)=N[C@H]2CC(NCCOCCOCCN(C(COC3=CC=CC([C@@H](CCC4=CC(OC)=C(OC)C=C4)OC([C@@H]5CCCCN5C([C@H](C6=CC(OC)=C(OC)C(OC)=C6)CC)=O)=O)=C3)=O)C)=O)=C(S7)N8C2=NN=C8C)=C7C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (81.91 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8191 mL | 4.0955 mL | 8.1909 mL | 20.4774 mL |
| 5 mM | 0.1638 mL | 0.8191 mL | 1.6382 mL | 4.0955 mL | |
| 10 mM | 0.0819 mL | 0.4095 mL | 0.8191 mL | 2.0477 mL | |
| 15 mM | 0.0546 mL | 0.2730 mL | 0.5461 mL | 1.3652 mL | |
| 20 mM | 0.0410 mL | 0.2048 mL | 0.4095 mL | 1.0239 mL | |
| 25 mM | 0.0328 mL | 0.1638 mL | 0.3276 mL | 0.8191 mL | |
| 30 mM | 0.0273 mL | 0.1365 mL | 0.2730 mL | 0.6826 mL | |
| 40 mM | 0.0205 mL | 0.1024 mL | 0.2048 mL | 0.5119 mL | |
| 50 mM | 0.0164 mL | 0.0819 mL | 0.1638 mL | 0.4095 mL | |
| 60 mM | 0.0137 mL | 0.0683 mL | 0.1365 mL | 0.3413 mL | |
| 80 mM | 0.0102 mL | 0.0512 mL | 0.1024 mL | 0.2560 mL |