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United States

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製品番号: HY-W748000

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Kocurin

Name: Kocurin
Brand: MedChemExpress
SKU: HY-W748000
Availability: PreOrder

(別名: PM181104; Baringolin)

Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1374772-61-8
分子式: C₆₉H₆₆N₁₈O₁₃S₅
分子量:1515.70

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Kocurin 構造式

CAS 番号: 1374772-61-8

容量

価格（税別）

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Antibiotic アイソフォーム固有の製品をすべて表示 :

体外実験

Kocurin (24 h) inhibits S. aureus with MICs in the range of 0.008 to 2.048 μg/mL and an MIC₉₀ value of 0.064 μg/mL^[1].
Kocurin (24 h) inhibits S. epidermidis with MICs in the range of 0.008 to 1.024 μg/mL and an MIC₉₀ value of 0.128 μg/mL^[1].
Kocurin (24 h) inhibits VRE and VSE strains with MICs in the range of 0.004 to 1.024 μg/mL and an MIC₉₀ value of 0.016 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Kocurin (1.25-10 mg/kg; intravenous injection; single dose) has the 100% effective dose (ED₁₀₀) values of 2.5 and 5.0 mg/kg for MRSA, and an ED₁₀₀ value of 10.0 mg/kg for VRE in the BALB/c mouse septicemia model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

化学情報

CAS 番号 1374772-61-8
分子量 1515.70
分子式 C₆₉H₆₆N₁₈O₁₃S₅
別名

PM181104; Baringolin
Structure Classification
- Peptides
- Extract
Initial Source
- Marine natural products
- Sponge
- Microorganism
Micrococcus spp.
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (291 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Mahajan G, et al. In vitro and in vivo activities of antibiotic PM181104. Antimicrob Agents Chemother. 2013 Nov;57(11):5315-9. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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