LMD-902
LMD-902, a LMD-009 (HY-121885) analog, is a CCR8 agonist with an EC50 of 15 nM. LMD-902 has a superior binging capacity depending on key residues such as PheVI:16. LMD-902 can be used for inflammation diseases like bronchial asthma and central nervous system diseases like multiple sclerosis research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 521979-59-9
- 分子式: C28H34N2O6S
- 分子量:526.64
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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CCR8 15 nM (EC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COS-7 | EC50 |
15 nM
Compound: 73; LMD-902
|
Antiproliferative activity against African green monkey COS7 cells assessed as inhibition of cell growth
Antiproliferative activity against African green monkey COS7 cells assessed as inhibition of cell growth
|
[PMID: 28165741] |
化学情報
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CAS 番号 521979-59-9
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分子量 526.64
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分子式 C28H34N2O6S
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SMILES
O=S(NCC)(C1=CC=C(C=C1C2(CCN(CC2)CC3=CC(OC4=C(OC)C=CC=C4)=CC=C3)O)OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)