NYLTHRQ
NYLTHRQ is a peptide. NYLTHRQ specifically blocks the interaction between sVEGFR1-i13 and β1 integrin, and inhibits the activation of VEGFR1 and VEGFR2. NYLTHRQ inhibits cancer cell proliferation. NYLTHRQ can be used in the research of tumors such as lung squamous cell carcinoma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1004284-41-6
- 分子式: C40H62N14O12
- 分子量:931.01
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
VEGFR アイソフォーム固有の製品をすべて表示
More
生物活性
|
VEGFR1 |
VEGFR2 |
NYLTHRQ (10 μg/mL; 72 h) specifically blocks the interaction between sVEGFR1-i13 and β1 integrin in MGH7 cells, inhibits VEGFR activation, and reduces cell proliferation activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:MGH7 squamous cell lung carcinoma (SQLC) cells
-
Concentration:10 μg/mL
-
Incubation Time:72 h
-
Result:Prevented the activation of VEGFR1 (Tyr1213) and VEGFR2 (Tyr1214) proteins.
Blocked the increased cell proliferation induced by sVEGFR1-i13-containing conditioned supernatants.
化学情報
-
CAS 番号 1004284-41-6
-
分子量 931.01
-
分子式 C40H62N14O12
-
配列
Asn-Tyr-Leu-Thr-His-Arg-Gln
-
シーケンスの短縮
NYLTHRQ
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)