Phortress
Based on 1 Customer Validation
Phortress is a high affinity AhR ligand that elicits antitumor activity by inducing transcription of CYP1A1.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.19%
- CAS 番号: 328087-38-3
- 分子式: C20H25Cl2FN4OS
- 分子量:459.41
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Metabolism/Protease Compound Library
HY-L012
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
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HY-L178
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生物活性
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CYP1 |
化学情報
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CAS 番号 328087-38-3
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性状 Solid
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分子量 459.41
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分子式 C20H25Cl2FN4OS
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Color Light yellow to yellow
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SMILES
O=C(NC1=CC=C(C2=NC3=CC(F)=CC=C3S2)C=C1C)[C@@H](N)CCCCN.[H]Cl.[H]Cl
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別名
NSC 710305
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 125 mg/mL (272.09 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Bradshaw TD, et al. In vitro evaluation of amino acid prodrugs of novel antitumour 2-(4-amino-3-methylphenyl)benzothiazoles. Br J Cancer. 2002 Apr 22;86(8):1348-54. [Content Brief]
[2]. Bradshaw TD, Westwell AD. The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate. Curr Med Chem. 2004 Apr;11(8):1009-21. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1767 mL | 10.8835 mL | 21.7670 mL | 54.4176 mL |
| 5 mM | 0.4353 mL | 2.1767 mL | 4.3534 mL | 10.8835 mL | |
| 10 mM | 0.2177 mL | 1.0884 mL | 2.1767 mL | 5.4418 mL | |
| 15 mM | 0.1451 mL | 0.7256 mL | 1.4511 mL | 3.6278 mL | |
| 20 mM | 0.1088 mL | 0.5442 mL | 1.0884 mL | 2.7209 mL | |
| 25 mM | 0.0871 mL | 0.4353 mL | 0.8707 mL | 2.1767 mL | |
| 30 mM | 0.0726 mL | 0.3628 mL | 0.7256 mL | 1.8139 mL | |
| 40 mM | 0.0544 mL | 0.2721 mL | 0.5442 mL | 1.3604 mL | |
| 50 mM | 0.0435 mL | 0.2177 mL | 0.4353 mL | 1.0884 mL | |
| 60 mM | 0.0363 mL | 0.1814 mL | 0.3628 mL | 0.9070 mL | |
| 80 mM | 0.0272 mL | 0.1360 mL | 0.2721 mL | 0.6802 mL | |
| 100 mM | 0.0218 mL | 0.1088 mL | 0.2177 mL | 0.5442 mL |
Phortress 関連分類
HY-103223 関連分類
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