VU6043653
Based on 1 Customer Validation
VU6043653 is a potent, selective and cross the blood-brain barrier metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 value of 325 nM for h mGlu5.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.97%
- CAS 番号: 3032791-06-0
- 分子式: C16H14FN5O2
- 分子量:327.31
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保管条件:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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human mGluR5 325 nM (IC50) |
化学情報
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CAS 番号 3032791-06-0
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性状 Solid
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分子量 327.31
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分子式 C16H14FN5O2
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Color Off-white to light yellow
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SMILES
CC1=NC(C(NC2=CC=C(F)C=N2)=O)=CC(OC3=CN(C)N=C3)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : ≥ 25 mg/mL (76.38 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0552 mL | 15.2760 mL | 30.5521 mL | 76.3802 mL |
| 5 mM | 0.6110 mL | 3.0552 mL | 6.1104 mL | 15.2760 mL | |
| 10 mM | 0.3055 mL | 1.5276 mL | 3.0552 mL | 7.6380 mL | |
| 15 mM | 0.2037 mL | 1.0184 mL | 2.0368 mL | 5.0920 mL | |
| 20 mM | 0.1528 mL | 0.7638 mL | 1.5276 mL | 3.8190 mL | |
| 25 mM | 0.1222 mL | 0.6110 mL | 1.2221 mL | 3.0552 mL | |
| 30 mM | 0.1018 mL | 0.5092 mL | 1.0184 mL | 2.5460 mL | |
| 40 mM | 0.0764 mL | 0.3819 mL | 0.7638 mL | 1.9095 mL | |
| 50 mM | 0.0611 mL | 0.3055 mL | 0.6110 mL | 1.5276 mL | |
| 60 mM | 0.0509 mL | 0.2546 mL | 0.5092 mL | 1.2730 mL |
VU6043653 関連分類
HY-169345 関連分類
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