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Glabridin

13 Cited Publications
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Based on 13 publication(s) in Google Scholar

Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities.

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  • Purity: 99.91%
  • CAS No.: 59870-68-7
  • 화학식: C20H20O4
  • 분자량:324.37
  • 보관:
    Powder   -20°C, 3 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Glabridin Chemical Structure
    Glabridin Chemical Structure
  • Experimental Validation Results for Glabridin
  • Experimental Validation Results for Glabridin
  • Experimental Validation Results for Glabridin
  • Experimental Validation Results for Glabridin
  • Experimental Validation Results for Glabridin
CAS No.: 59870-68-7
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  • Glabridin Chemical Structure
    Glabridin Chemical Structure
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  • 1/16

    Glabridin purchased from MedChemExpress. Usage Cited in: Parasit Vectors. 2024 Dec 18;17(1):522. [Abstract]

    Customer Validation
     Cytotoxicity of Glabridin on Vero cells. Glabridin demonstrated low cytotoxicity in Vero cells. Cells were exposed to increasing concentrations of Glabridin (0, 2.5, 5, 7.5, 10, and 20 µg/mL) for 24 h. Cell viability was measured using the Cell Counting Kit-8 (CCK-8) assay, with results expressed as a percentage relative to the untreated control group.

  • 1/16

    Glabridin purchased from MedChemExpress. Usage Cited in: Mol Med. 2023 Dec 8;29(1):167. [Abstract]

    Customer Validation
     BMDMs were first treated with DMSO or Glabridin (Glab) (0. 5, 10, 20 μM) of various concentrations for 1 h, and then stimulated with HT-DNA or Poly(I:C) for 2 h. Whole cell lysate (WCL) was collected and immunoblotted with the indicated antibody.

  • 1/16

    Glabridin purchased from MedChemExpress. Usage Cited in: Mol Med. 2023 Dec 8;29(1):167. [Abstract]

    Customer Validation
     BMDMs were treated with DMSO or Glabridin (Glab) (0. 5, 10, 20 μM) of various concentrations for 1 h, and then stimulated with HT-DNA for 4 h. The expression of IFN-β, IL-6 and TNF-α mRNA level were detected by quantitative polymerase chain reaction (qPCR) assay.

  • 1/16

    Glabridin purchased from MedChemExpress. Usage Cited in: Mol Med. 2023 Dec 8;29(1):167. [Abstract]

    Customer Validation
     Glabridin (20, 40 mg/kg, i.p.) (Glab) inhibits the activation of STING and downstream signaling pathway in vivo. Determination of IFN-β, IL-6 and TNF-α concentrations in collected serum by ELISA kits.

  • 1/16

    Glabridin purchased from MedChemExpress. Usage Cited in: Mol Med. 2023 Dec 8;29(1):167. [Abstract]

    Customer Validation
     Representative images of various tissues stained with hematoxylin–eosin (H&E) staining. Glabridin (20, 40 mg/kg, i.p.) (Glab) Alleviates the Autoinfammatory Response in Trex1−/− Mice.

  • Glabridin