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Cat. No.: HY-118848

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A63162

A63162 is a specific 5-lipoxygenase (5-LOX) inhibitor. A63162 inhibits mitogen (PHA)-induced horse mononuclear cell (BMC) proliferation and inhibits Calcimycin (HY-N6687)-induced leukotriene LTB4 synthesis at the same concentration. A63162 can be used in the study of chronic obstructive pulmonary disease, arthritis and inflammatory bowel disease.

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CAS No.: 111525-11-2
화학식: C₁₇H₁₉NO₃
분자량:285.34

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

A63162 Chemical Structure

CAS No.: 111525-11-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Lipoxygenase Isoforms :

All Leukotriene Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
RBL-1	IC₅₀	0.37 μM Compound: 4b	In vitro inhibition of 5-lipoxygenase in RBL-1 cells In vitro inhibition of 5-lipoxygenase in RBL-1 cells	[PMID: 3336029]

Chemical Information

CAS No. 111525-11-2
분자량 285.34
화학식 C₁₇H₁₉NO₃
SMILES

CC(N(C(C)C1=CC=C(C=C1)OCC2=CC=CC=C2)O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Olsen S C, et al. Inhibition of equine mononuclear cell proliferation and leukotriene B4 synthesis by a specific 5-lipoxygenase inhibitor, A-63162[J]. American journal of veterinary research, 1992, 53(6): 1015-1018. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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A63162

All Lipoxygenase Isoforms

All Leukotriene Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

A63162 Related Classifications

HY-118848 Related Classifications