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AKN-028 TFA

AKN-028 TFA, a novel tyrosine kinase (TK) inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. AKN-028 TFA inhibits FLT3 autophosphorylation. AKN-028 TFA induces dose-dependent cytotoxic response (mean IC50=1 μM). AKN-028 TFA induces apoptosisby activation of caspase 3. AKN-028 TFA can be used in research of acute myeloid leukemia (AML).

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  • CAS No.: 1175017-91-0
  • 화학식: C19H15F3N6O2
  • 분자량:416.36
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AKN-028 TFA Chemical Structure
    AKN-028 TFA Chemical Structure
CAS No.: 1175017-91-0
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  • AKN-028 TFA Chemical Structure
    AKN-028 TFA Chemical Structure
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  • AKN-028 TFA