Bleomycin B4
Based on 1 Customer Validation
Bleomycin B4 (Phleomycin F) is an antibiotic. Bleomycin B4 has antitumor activity. Bleomycin B4 can be used for the research of cancer.
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- Purity: 98.71%
- CAS No.: 9060-11-1
- 화학식: C60H95N23O21S2
- 분자량:1538.67
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All Antibiotic Isoforms
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Biological Activity
Chemical Information
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CAS No. 9060-11-1
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Appearance Solid
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분자량 1538.67
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화학식 C60H95N23O21S2
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Color White to off-white
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SMILES
O[C@H]1[C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]2[C@H](O[C@H]([C@H](NC(C3=C(C)C(N)=NC([C@@H](NC[C@H](C(N)=O)N)CC(N)=O)=N3)=O)C(N[C@@H]([C@@H](O)[C@@H](C(N[C@H](C(NCCC4=NC(C5=NC(C(NCCCCN(C(N)=N)CCCCNC(N)=N)=O)=CS5)=CS4)=O)[C@H](O)C)=O)C)C)=O)C6=CNC=N6)O[C@@H](CO)[C@@H](O)[C@@H]2O
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Synonyms
Phleomycin F
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Structure Classification
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Initial Source
Streptoverticillium griseocarneum bleomycini 1129/2646
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
DMSO : 25 mg/mL (16.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. T P Korobkova, et al. Optimization of the nutrient medium makeup for the biosynthesis of bleomycine antibiotic using a mathematical method of experimental design. Antibiotiki. 1978 Dec;23(12):1065-8. [Content Brief]
[2]. V A Zenkova, et al. Physicochemical and biological properties of bleomycin complex antibiotics. Antibiotiki. 1979 Mar;24(3):175-9. [Content Brief]
[3]. A Yagoda, et al. Bleomycin, an antitumor antibiotic. Clinical experience in 274 patients. Ann Intern Med. 1972 Dec;77(6):861-70. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6499 mL | 3.2496 mL | 6.4991 mL | 16.2478 mL |
| 5 mM | 0.1300 mL | 0.6499 mL | 1.2998 mL | 3.2496 mL | |
| 10 mM | 0.0650 mL | 0.3250 mL | 0.6499 mL | 1.6248 mL | |
| 15 mM | 0.0433 mL | 0.2166 mL | 0.4333 mL | 1.0832 mL |