Desotamide
Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).
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- CAS No.: 194660-14-5
- 화학식: C35H52N8O7
- 분자량:696.84
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
|
[PMID: 25072108] |
| MCF7 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
|
[PMID: 25072108] |
| NCI-H460 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human NCI-H460 after 72 hrs by SRB assay
Cytotoxicity against human NCI-H460 after 72 hrs by SRB assay
|
[PMID: 25072108] |
| SF-268 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human SF268 cells after 72 hrs by SRB assay
Cytotoxicity against human SF268 cells after 72 hrs by SRB assay
|
[PMID: 25072108] |
Chemical Information
-
CAS No. 194660-14-5
-
분자량 696.84
-
화학식 C35H52N8O7
-
Synonyms
Desotamide A
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Sequence
cyclo(Asn-Gly-Trp-Leu-Leu-Ile)
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Sequence Shortening
cyclo(NGWLLI)
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)