Esculentoside B
Based on 1 Customer Validation
Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity.
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- Purity: 99.88%
- CAS No.: 60820-94-2
- 화학식: C36H56O11
- 분자량:664.82
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
74.7 μM
Compound: 9
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Cytotoxicity against human HepG2 cells
Cytotoxicity against human HepG2 cells
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[PMID: 18177012] |
| WI-38 | IC50 |
36.2 μM
Compound: 9
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Cytotoxicity against human WI38 cells
Cytotoxicity against human WI38 cells
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[PMID: 18177012] |
| WI-38 VA13 | IC50 |
68.9 μM
Compound: 9
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Cytotoxicity against human VA13 cells
Cytotoxicity against human VA13 cells
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[PMID: 18177012] |
Chemical Information
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CAS No. 60820-94-2
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Appearance Solid
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분자량 664.82
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화학식 C36H56O11
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Color White to off-white
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SMILES
C[C@@]12C([C@@]3([H])[C@](C(O)=O)(CC[C@@](C(OC)=O)(C)C3)CC2)=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(C[C@H](O)[C@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O)CO6)O)O)[C@@]5(C)CO)C)C
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Synonyms
Phytolaccoside B
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
순도&문서
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Abekura F, et al. Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells. Int Immunopharmacol. 2019;68:156-163. [Content Brief]
[2]. Ren S, et al. Metabolic exploration of the developmental abnormalities and neurotoxicity of Esculentoside B, the main toxic factor in Phytolaccae radix. Food Chem Toxicol. 2023;176:113777. [Content Brief]
[3]. Escalante A, et al. Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. J Nat Prod. 2008;71(10):1720-1725. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Esculentoside B Related Classifications
HY-N6032 Related Classifications
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