Folic acid-d2
Based on 1 Customer Validation
Folic acid-d2 (Vitamin B9-d2) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
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- Purity: 97.86%
- CAS No.: 69022-87-3
- 화학식: C19H17D2N7O6
- 분자량:443.41
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 69022-87-3
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Unlabeled Cas 59-30-3
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Appearance Solid
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분자량 443.41
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화학식 C19H17D2N7O6
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Color Light yellow to yellow
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SMILES
O=C1C2=NC(C([2H])([2H])NC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)=CNC2=NC(N)=N1
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Synonyms
Vitamin B9-d2; Vitamin M-d2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 33.33 mg/mL (75.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2552 mL | 11.2762 mL | 22.5525 mL | 56.3812 mL |
| 5 mM | 0.4510 mL | 2.2552 mL | 4.5105 mL | 11.2762 mL | |
| 10 mM | 0.2255 mL | 1.1276 mL | 2.2552 mL | 5.6381 mL | |
| 15 mM | 0.1503 mL | 0.7517 mL | 1.5035 mL | 3.7587 mL | |
| 20 mM | 0.1128 mL | 0.5638 mL | 1.1276 mL | 2.8191 mL | |
| 25 mM | 0.0902 mL | 0.4510 mL | 0.9021 mL | 2.2552 mL | |
| 30 mM | 0.0752 mL | 0.3759 mL | 0.7517 mL | 1.8794 mL | |
| 40 mM | 0.0564 mL | 0.2819 mL | 0.5638 mL | 1.4095 mL | |
| 50 mM | 0.0451 mL | 0.2255 mL | 0.4510 mL | 1.1276 mL | |
| 60 mM | 0.0376 mL | 0.1879 mL | 0.3759 mL | 0.9397 mL |
Folic acid-d2 Related Classifications
HY-16637S Related Classifications
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