LCE4A - late cornified envelope 4A Gene
Also Known as LEP8; SPRL4A
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 199834
Summary
Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Jul 2025]
LCE4A Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001387222.1 | NP_001374151.1 | late cornified envelope protein 4A |
| NM_178356.3 | NP_848133.1 | late cornified envelope protein 4A |
Compound Screening Libraries
Virtual Screening
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Drug Screening Service
LCE4A Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-8 | Homo sapiens | P60410 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-8 | Homo sapiens | P60410 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-8 | Homo sapiens | P60410 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-8 | Homo sapiens | P60410 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-8 | Homo sapiens | P60410 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-9 | Homo sapiens | P60411 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-5 | Homo sapiens | P60370 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-7 | Homo sapiens | P60409 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-7 | Homo sapiens | P60409 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-7 | Homo sapiens | P60409 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP12-2 | Homo sapiens | P59991 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP12-2 | Homo sapiens | P59991 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | RGS20 | Homo sapiens | O76081-6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | RGS20 | Homo sapiens | O76081-6 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | RGS20 | Homo sapiens | O76081-6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | RGS20 | Homo sapiens | O76081-6 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-4 | Homo sapiens | Q9BYQ2 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-4 | Homo sapiens | Q9BYQ2 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | LCE1B | Homo sapiens | Q5T7P3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE1B | Homo sapiens | Q5T7P3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-2 | Homo sapiens | Q9BYQ4 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-2 | Homo sapiens | Q9BYQ4 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-2 | Homo sapiens | Q9BYQ4 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-2 | Homo sapiens | Q9BYQ4 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | VASN | Homo sapiens | Q6EMK4 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | VASN | Homo sapiens | Q6EMK4 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | VASN | Homo sapiens | Q6EMK4 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-6 | Homo sapiens | Q6L8G9 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-11 | Homo sapiens | Q9BYQ6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-11 | Homo sapiens | Q9BYQ6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-11 | Homo sapiens | Q9BYQ6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | SLC39A7 | Homo sapiens | Q92504 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | RGS20 | Homo sapiens | O76081 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP1-3 | Homo sapiens | Q8IUG1 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP1-3 | Homo sapiens | Q8IUG1 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP12-3 | Homo sapiens | P60328 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP12-3 | Homo sapiens | P60328 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE1E | Homo sapiens | Q5T753 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE1E | Homo sapiens | Q5T753 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE5A | Homo sapiens | Q5TCM9 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE5A | Homo sapiens | Q5TCM9 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE5A | Homo sapiens | Q5TCM9 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-4 | Homo sapiens | Q9BYR3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-8 | Homo sapiens | Q9BYQ0 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-8 | Homo sapiens | Q9BYQ0 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP9-8 | Homo sapiens | Q9BYQ0 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP1-1 | Homo sapiens | Q07627 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP1-1 | Homo sapiens | Q07627 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-4 | Homo sapiens | Q6L8H1 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE2C | Homo sapiens | Q5TA81 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE2C | Homo sapiens | Q5TA81 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE2C | Homo sapiens | Q5TA81 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-3 | Homo sapiens | Q6L8H2 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-7 | Homo sapiens | Q6L8G8 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-7 | Homo sapiens | Q6L8G8 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-7 | Homo sapiens | Q6L8G8 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP17-1 | Homo sapiens | Q9BYP8 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP17-1 | Homo sapiens | Q9BYP8 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP17-1 | Homo sapiens | Q9BYP8 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-5 | Homo sapiens | Q9BYR2 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-11 | Homo sapiens | Q6L8G4 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-6 | Homo sapiens | P60371 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP10-6 | Homo sapiens | P60371 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE1C | Homo sapiens | Q5T751 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | LCE1C | Homo sapiens | Q5T751 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | RNF111 | Homo sapiens | Q6ZNA4 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | RNF111 | Homo sapiens | Q6ZNA4 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | RNF111 | Homo sapiens | Q6ZNA4 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | NOTCH2NLC | Homo sapiens | P0DPK4 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | NOTCH2NLC | Homo sapiens | P0DPK4 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | TGM1 | Homo sapiens | P22735 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | TGM1 | Homo sapiens | P22735 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | CYSRT1 | Homo sapiens | A8MQ03 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | CYSRT1 | Homo sapiens | A8MQ03 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | RGS17 | Homo sapiens | Q9UGC6 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | HSD3B7 | Homo sapiens | Q9H2F3 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-3 | Homo sapiens | Q9BYR6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-3 | Homo sapiens | Q9BYR6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-3 | Homo sapiens | Q9BYR6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-9 | Homo sapiens | P26371 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-9 | Homo sapiens | P26371 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-9 | Homo sapiens | P26371 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-9 | Homo sapiens | P26371 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP5-9 | Homo sapiens | P26371 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | P4HB | Homo sapiens | P07237 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | P4HB | Homo sapiens | P07237 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | ZNF655 | Homo sapiens | Q8N720 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | ZNF655 | Homo sapiens | Q8N720 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | ZNF655 | Homo sapiens | Q8N720 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | CRCT1 | Homo sapiens | Q9UGL9 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | MDFI | Homo sapiens | Q99750 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | MDFI | Homo sapiens | Q99750 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | PLSCR1 | Homo sapiens | O15162 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | PLSCR1 | Homo sapiens | O15162 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | HOXA1 | Homo sapiens | P49639 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | HOXA1 | Homo sapiens | P49639 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | HOXA1 | Homo sapiens | P49639 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | SPRY2 | Homo sapiens | O43597 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | MEOX2 | Homo sapiens | P50222 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | MEOX2 | Homo sapiens | P50222 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | SMCP | Homo sapiens | P49901 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | SMCP | Homo sapiens | P49901 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | PLSCR3 | Homo sapiens | Q9NRY6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | PLSCR3 | Homo sapiens | Q9NRY6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | PLSCR3 | Homo sapiens | Q9NRY6 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | TSPAN4 | Homo sapiens | O14817 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | TSPAN4 | Homo sapiens | O14817 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | RGS19 | Homo sapiens | P49795 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | RGS19 | Homo sapiens | P49795 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | FUCA2 | Homo sapiens | Q9BTY2 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | FUCA2 | Homo sapiens | Q9BTY2 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | FUCA2 | Homo sapiens | Q9BTY2 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRT31 | Homo sapiens | Q15323 | 25416956 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-1 | Homo sapiens | Q9BYR8 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-1 | Homo sapiens | Q9BYR8 | 32296183 | |
|
Intra
|
LCE4A | Q5TA78 | KRTAP3-1 | Homo sapiens | Q9BYR8 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction