country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-185345

Copy Link Print Information

GR119566X

GR119566X is a 5-HT₃ receptor ligand with a pK_i value of 8.80 against prufied 5-HT₃ receptor. GR119566X can be used for 5-HT₃ receptor purification.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 237752-42-0
화학식: C₂₀H₂₄N₄O
분자량:336.43

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

GR119566X Chemical Structure

CAS No.: 237752-42-0

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

GR119566X is a 5-HT₃ receptor ligand with a pK_i value of 8.80 against prufied 5-HT₃ receptor. GR119566X can be used for 5-HT₃ receptor purification^[1].

IC₅₀ & Target

5-HT₃ Receptor

All 5-HT Receptor Isoforms :

In Vitro

GR119566X (12.5 mg; 16 h) is successfully coupled to Aﬃ-Gel 15 to form an affinity resin that specifically retains solubilized 5-HT₃ receptors from porcine cerebral cortex, enabling receptor purification^[1].
GR119566X (60 min at 37°C) binds to membrane-bound, solubilized, and affinity-purified 5-HT₃ receptors from porcine cerebral cortex with consistent high affinity, as shown by pK_i values ranging from 8.21 to 8.80^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 237752-42-0
분자량 336.43
화학식 C₂₀H₂₄N₄O
SMILES

NCCCN1C(CCC(C2=O)CC3=C(N=CN3)C)=C2C4=C1C=CC=C4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Fletcher S, et al. Purification of 5-hydroxytryptamine3 receptors from porcine brain. Br J Pharmacol. 1997 Oct;122(4):655-62. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

견적 받기 해외재고보유

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

GR119566X

High-Throughput Bioactive Compound Library

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

GR119566X Related Classifications

HY-185345 Related Classifications