Holomycin
Based on 1 Customer Validation
Holomycin is an antibiotic with dithiolopyrrolone structure. Holomycin can inhibit bacterial RNA synthesis. Holomycin has antitumor activity. Holomycin can be used for the research of bacterial infection.
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- Purity: 95.09%
- CAS No.: 488-04-0
- 화학식: C7H6N2O2S2
- 분자량:214.26
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보관:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Holomycin is a broad-spectrum antibiotic that inhibits RNA synthesis in cultured Escherichia coli, acts against Rifampicin (HY-B0272)-resistant Staphylococcus aureus, and lacks activity against Saccharomyces cerevisiae[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 488-04-0
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Appearance Solid
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분자량 214.26
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화학식 C7H6N2O2S2
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Color Light yellow to brown
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SMILES
CC(NC1=C2C(NC1=O)=CSS2)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
순도&문서
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Holomycin
- 488-04-0
- Antibiotic
- Bacterial
- DNA/RNA Synthesis
- clavulanic acid biosynthesis genes
- dithiol oxidase HlmI
- Escherichia coli
- Staphylococcus aureus
- rifampicin-resistant mutants
- RNA polymerase β-subunit
- Yersinia ruckeri
- prokaryotic RNA polymerase
- Streptomyces clavuligerus
- Saccharomyces cerevisiae
- Inhibitor
- inhibitor
- inhibit