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Cat. No.: HY-P10988

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LVTX-8

LVTX-8 is a peptide toxin, exacted from Lycosa vittata. LVTX-8 has potent anticancer and and anti-metastasis activities towards lung cancer with strong cytotoxicity. LVTX-8 significantly induces apoptosis and inhibits the proliferation, invasion and migration of lung cancer cells through P53 hypoxia pathways and integrin signaling. LVTX-8 significantly inhibits the tumor growth and metastasis in A549/H460 xenograft mice model.

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CAS No.: 2197957-07-4
화학식: C₁₃₅H₂₂₆N₃₆O₃₁
분자량:2849.46

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

LVTX-8 Chemical Structure

CAS No.: 2197957-07-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Integrin Isoforms :

Chemical Information

CAS No. 2197957-07-4
분자량 2849.46
화학식 C₁₃₅H₂₂₆N₃₆O₃₁
Sequence

Ile-Trp-Leu-Thr-Ala-Leu-Lys-Phe-Leu-Gly-Lys-Asn-Leu-Gly-Lys-His-Leu-Ala-Lys-Gln-Gln-Leu-Ser-Lys-Leu
Sequence Shortening

IWLTALKFLGKNLGKHLAKQQLSKL
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang P, et al. An Anti-Cancer Peptide LVTX-8 Inhibits the Proliferation and Migration of Lung Tumor Cells by Regulating Causal Genes' Expression in p53-Related Pathways. Toxins (Basel). 2020 Jun 2;12(6):367. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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LVTX-8

All Integrin Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

LVTX-8 Related Classifications

HY-P10988 Related Classifications