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Cat. No.: HY-172924

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NLX-266

NLX-266 is an orally active ERK1/2-biased 5-HT_1A receptor agonist. NLX-266 can be used in the study of Parkinson's disease.

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CAS No.: 2170564-20-0
화학식: C₂₀H₂₁ClF₃N₃O₂
분자량:427.85

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

NLX-266 Chemical Structure

CAS No.: 2170564-20-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
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Biological Activity

제품 설명

NLX-266 is an orally active ERK1/2-biased 5-HT_1A receptor agonist. NLX-266 can be used in the study of Parkinson's disease^[1].

IC₅₀ & Target

5-HT_1A Receptor

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 2170564-20-0
분자량 427.85
화학식 C₂₀H₂₁ClF₃N₃O₂
SMILES

O=C(C1=CC=C(F)C(Cl)=C1)N2CCC(CNCCOC3=NC=CC(F)=C3)(F)CC2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sniecikowska J, et al. Discovery of NLX-266, an Orally Available and Metabolically Stable ERK1/2-Biased 5-HT1AR Agonist with Superior Antidepressant and Antiparkinsonian Activity. J Med Chem. 2025 May 8;68(9):9706-9722. [Content Brief]

Calculators

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Concentration Concentration

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Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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NLX-266

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

NLX-266 Related Classifications

HY-172924 Related Classifications