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Cat. No.: HY-121738

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TC AC 28

TC AC 28 is a high-affinity BET bromodomain ligand with K_d values of 40, 800 nM for Brd2(2), Brd2(1), respectively.

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CAS No.: 1809296-92-1
화학식: C₂₃H₂₁N₅O₃
분자량:415.44

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

TC AC 28 Chemical Structure

CAS No.: 1809296-92-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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제품 설명

TC AC 28 is a high-affinity BET bromodomain ligand with K_d values of 40, 800 nM for Brd2(2), Brd2(1), respectively^[1].

IC₅₀ & Target^[1]

BRD2(1)

40 nM (Kd)

BRD2(2)

800 nM (EC₅₀)

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Chemical Information

CAS No. 1809296-92-1
분자량 415.44
화학식 C₂₃H₂₁N₅O₃
SMILES

COC(CC1N=C(C2=C3C=CNC3=CC=C2)C4=CC(OC)=CC=C4N5C(C)=NN=C15)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Khan R, et al. Gram-Scale Laboratory Synthesis of TC AC 28, a High-Affinity BET Bromodomain Ligand. ACS Omega. 2017 Aug 8;2(8):4328-4332. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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TC AC 28

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Biological Activity

Chemical Information

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References

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TC AC 28 Related Classifications

HY-121738 Related Classifications