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Cat. No.: HY-106515

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Tebuquine

(Synonyms: WR228258)

Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine (HY-17589A) sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC₅₀s of 0.9 nM and 20.8 nM, respectively.

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CAS No.: 74129-03-6
화학식: C₂₆H₂₅Cl₂N₃O
분자량:466.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Tebuquine Chemical Structure

CAS No.: 74129-03-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
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References
Calculators
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Classifications
Bioz

Biological Activity

제품 설명

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
J774	IC₅₀	1.8 μg/mL Compound: tebuquine	Toxicity against murine J774 macrophage cells Toxicity against murine J774 macrophage cells	[PMID: 17266295]

Chemical Information

CAS No. 74129-03-6
분자량 466.40
화학식 C₂₆H₂₅Cl₂N₃O
SMILES

ClC1=CC=C(C2=CC(NC3=C4C=CC(Cl)=CC4=NC=C3)=CC(CNC(C)(C)C)=C2O)C=C1
Synonyms

WR228258
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. P M O'Neill, et al. Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues. J Med Chem. 1997 Feb 14;40(4):437-48. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Tebuquine

All Parasite Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Tebuquine Related Classifications

HY-106515 Related Classifications