TOP1288
TOP1288 is a narrow spectrum kinase inhibitor for P38α, Src and Syk kinase, with IC50 of 116nM, 24nM and 659nM, respectively. TOP1288 inhibits inflammatory cytokine release from inflamed biopsies and myofibroblasts.
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- CAS No.: 1630202-02-6
- 화학식: C43H49N7O9S
- 분자량:839.96
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
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Help & FAQs
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HY-12067
R406
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HY-11108
R406 free base
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HY-13038
Fostamatinib Disodium
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HY-100867A
Mivavotinib monohydrochloride
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HY-12736A
GSK143 dihydrochloride
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HY-13038R
Fostamatinib Disodium (Standard)
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HY-100867
Mivavotinib
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HY-100867AR
Mivavotinib monohydrochloride (Standard)
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HY-12736
GSK143
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HY-145029
SYK/JAK-IN-1
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HY-120214
TAS05567
Biological Activity
IC50: 24 nM (Src), 116 nM (P38α), 659 nM (Syk)
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1630202-02-6
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분자량 839.96
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화학식 C43H49N7O9S
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SMILES
O=C(NC1=CC(C(C)(C)C)=CC(NS(=O)(C)=O)=C1OC)NC2=CC=C(C3=C2C=CC=C3)OC4=NC(NC5=CC(C#C)=CC(C(NCCOCCOCCOC)=O)=C5)=NC=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TOP1288 Related Classifications
HY-160930 Related Classifications
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