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Cat. No.: HY-142953

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UNC6349 (Ket2)

UNC6349 (Ket2), a diethyllysine (Ket2)-containing ligand, binds to wild-type CBX5, with a K_D of 3.2 μM.

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화학식: C₄₁H₅₇N₇O₁₁
분자량:823.93

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (257 KB)

UNC6349 (Ket2) Chemical Structure

사이즈

가격

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

UNC6349 (Ket2), a diethyllysine (Ket2)-containing ligand, binds to wild-type CBX5, with a K_D of 3.2 μM^[1].

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Chemical Information

분자량 823.93
화학식 C₄₁H₅₇N₇O₁₁
SMILES

O=C(C1=COC=C1)NC([C@@H](O)C2=CC=CC=C2)C(N[C@@H](C)C(N[C@@H](CC3=CC=C(OC)C(OC)=C3)C(N[C@H](C(N[C@@H](CO)C(N)=O)=O)CCCCN(CC)CC)=O)=O)=O
Sequence

3-Furoic acid-3-Phenyl-L-Serine -Ala-Phe(3,4-Dimethoxy)-Lys(Et)2-Ser
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kean KM, et al. Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding. J Med Chem. 2022;65(3):2646-2655. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
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Chemical Information
순도&문서
References

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UNC6349 (Ket2)

All Epigenetic Reader Domain Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

UNC6349 (Ket2) Related Classifications

HY-142953 Related Classifications