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  3. M‑89

M‑89 

Cat. No.: HY-128347
Handling Instructions

M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia.

For research use only. We do not sell to patients.

M‑89 Chemical Structure

M‑89 Chemical Structure

CAS No. : 2363165-42-6

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Description

M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia[1].

IC50 & Target

Kd: 1.4 nM (menin)[1].

Molecular Weight

657.87

Formula

C₃₇H₄₇N₅O₄S

CAS No.

2363165-42-6

SMILES

O=C(OC)N[[email protected]@H]1[[email protected]@H]([[email protected]]2(C3CCN(CC4CN(C5=CC=C(S(=O)(C6=CC=NC=C6)=O)C=C5)C4)CC3)CN(C)CC7=C2C=CC=C7)CCC1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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M‑89
Cat. No.:
HY-128347
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