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Cat. No.: HY-124482

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Mesembrenol

Mesembrenol is an alkaloid inhibitor of serotonin transporters and PDE4. Mesembrenol also inhibits glutamatergic AMPA receptors and can be used in research on mild to moderate depression.

For research use only. We do not sell to patients.

CAS No.: 25516-15-8
Formula: C₁₇H₂₃NO₃
Molecular Weight:289.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (288 KB)

Mesembrenol Chemical Structure

CAS No.: 25516-15-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
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Biological Activity

Description

Mesembrenol is an alkaloid inhibitor of serotonin transporters and PDE4. Mesembrenol also inhibits glutamatergic AMPA receptors and can be used in research on mild to moderate depression^[1].

IC₅₀ & Target

^[2]

PDE4

All Phosphodiesterase (PDE) Isoforms :

All iGluR Isoforms :

Chemical Information

CAS No. 25516-15-8
Molecular Weight 289.37
Formula C₁₇H₂₃NO₃
SMILES

O[C@@H]1C=C[C@]2(CCN([C@]2(C1)[H])C)C3=CC=C(C(OC)=C3)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (288 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Alan Harvey et al. Use of pharmaceutical compositions containing mesembrenone. US8552051B2. 2010-03-16.

[2]. Gericke J et al. Sceletium tortuosum-derived mesembrine significantly contributes to the anxiolytic effect of Zembrin®, but its anti-depressant effect may require synergy of multiple plant constituents[J]. Journal of Ethnopharmacology, 2024, 319: 117113.

[3]. Dimpfel W et al. Effect of Zembrin® and four of its alkaloid constituents on electric excitability of the rat hippocampus[J]. Journal of ethnopharmacology, 2018, 223: 135-141.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Mesembrenol

All Phosphodiesterase (PDE) Isoforms

All iGluR Isoforms

Biological Activity

Description

IC50 & Target

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Mesembrenol Related Classifications

HY-124482 Related Classifications

Bioz

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