IS4

IS4 is a selective CXCR4 competitive antagonist, with an IC50 of 0.65 nM in THP-1 cells and 38.75 nM in Jurkat cells. IS4 is stable in serum and non-cytotoxic. IS4 competitively binds to CXCR4 with CXCL12, thereby inhibiting CXCL12-induced intracellular Ca2+ release and cancer cell migration. IS4 can be used in the research on the prevention of metastasis of breast cancer, prostate cancer, leukemia, and other diseases.

For research use only. We do not sell to patients.

  • CAS No.: 3067986-23-3
  • Formula: C48H62N14O11S2
  • Molecular Weight:1075.22
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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