Nrf2 activator-1
Based on 1 Customer Validation
Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1).
For research use only. We do not sell to patients.
- Purity: 98.66%
- CAS No.: 2230697-41-1
- Formula: C30H34N4O6S
- Molecular Weight:578.68
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Nrf2[1]
Chemical Information
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CAS No. 2230697-41-1
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Appearance Solid
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Molecular Weight 578.68
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Formula C30H34N4O6S
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Color White to yellow
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SMILES
CCOC(C[C@@H](C1=CC(CN2S(=O)(C3=CC=CC=C3O[C@@H](C2)C)=O)=C(C=C1)C)C4=CC(OC)=C(N(N=N5)C)C5=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (172.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7281 mL | 8.6404 mL | 17.2807 mL | 43.2018 mL |
| 5 mM | 0.3456 mL | 1.7281 mL | 3.4561 mL | 8.6404 mL | |
| 10 mM | 0.1728 mL | 0.8640 mL | 1.7281 mL | 4.3202 mL | |
| 15 mM | 0.1152 mL | 0.5760 mL | 1.1520 mL | 2.8801 mL | |
| 20 mM | 0.0864 mL | 0.4320 mL | 0.8640 mL | 2.1601 mL | |
| 25 mM | 0.0691 mL | 0.3456 mL | 0.6912 mL | 1.7281 mL | |
| 30 mM | 0.0576 mL | 0.2880 mL | 0.5760 mL | 1.4401 mL | |
| 40 mM | 0.0432 mL | 0.2160 mL | 0.4320 mL | 1.0800 mL | |
| 50 mM | 0.0346 mL | 0.1728 mL | 0.3456 mL | 0.8640 mL | |
| 60 mM | 0.0288 mL | 0.1440 mL | 0.2880 mL | 0.7200 mL | |
| 80 mM | 0.0216 mL | 0.1080 mL | 0.2160 mL | 0.5400 mL | |
| 100 mM | 0.0173 mL | 0.0864 mL | 0.1728 mL | 0.4320 mL |