NHTD
NHTD is a KRAS-PDEδ inhibitor. NHTD targets the prenyl-binding pocket of PDEδ, altering the cellular localization of KRAS, thereby inhibiting the proliferation of KRAS-mutant cancer cells and inducing apoptosis. NHTD can be used for research on KRAS-driven non-small cell lung cancer (NSCLC).
For research use only. We do not sell to patients.
- CAS No.: 2540915-70-4
- Formula: C24H26N2O5
- Molecular Weight:422.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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K-RAS |
Chemical Information
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CAS No. 2540915-70-4
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Molecular Weight 422.47
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Formula C24H26N2O5
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SMILES
CC(C)(C)C1=C(O)C(/C=N/NC(C2=C(O)C=C(O)C=C2)=O)=C(C(CCCC3)=C3O4)C4=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)