Stephanine
Based on 1 publication(s) in Google Scholar
Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer.
For research use only. We do not sell to patients.
- CAS No.: 517-63-5
- Formula: C19H19NO3
- Molecular Weight:309.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Stephanine
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Biological Activity
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Cell Line
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Type | Value | Description | References |
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| BV-2 | IC50 |
20.26 μM
Compound: 11
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Inhibition of NO production in LPS-induced mouse BV-2 cells incubated for 24 hrs by Griess reagent based microplate reader analysis
Inhibition of NO production in LPS-induced mouse BV-2 cells incubated for 24 hrs by Griess reagent based microplate reader analysis
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[PMID: 37172474] |
Chemical Information
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CAS No. 517-63-5
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Molecular Weight 309.36
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Formula C19H19NO3
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SMILES
CN1CCC(C2=C3C4=CC=CC(OC)=C4C[C@@]12[H])=CC5=C3OCO5
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Synonyms
(-)-Stephanine; l-Stephanine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Vet Microbiol
Antiviral activity of Stephania japonica extract against porcine epidemic diarrhea virus infection. [Abstract]2025 Sep:308:110647. PMID: 40706130
Purity & Documentation
References
[1]. Cui L, et, al. The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo. Front Pharmacol. 2023 Jan 4;13:1092583. [Content Brief]
[2]. Le PM, et, al. Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit. Phytother Res. 2017 Sep;31(9):1357-1368. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Stephanine Related Classifications
HY-N1219 Related Classifications
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