319 Results for "

male broilers

" in MedChemExpress (MCE) Product Catalog:
Products (319)

319 Results for "male broilers" in MCE Product Catalog:

Cat. No.: HY-118424
CAS No.: 2036081-86-2
Target:  

iGluR

JNJ-55511118 is a selective TARP γ-8 binding AMPA receptor modulator with oral bioavailability and blood-brain barrier permeability, with a Ki of 26 nM. JNJ-55511118 reduces voluntary intake of sweetened alcohol in male mice. In rodent models, JNJ-55511118 inhibits hippocampal neurotransmission, reduces specific electroencephalogram frequency bands, induces transient hyperlocomotion, impairs learning and memory abilities, and exerts anticonvulsant effects. JNJ-55511118 is applicable to research related to alcohol use disorder and seizures .
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Cat. No.: HY-133676
CAS No.: 40321-98-0
Synonyms: MEOHP; 5-oxo-MEHP
Research Areas:  

Endocrinology

Mono (2-ethyl-5-oxohexyl) phthalate (MEOHP; 5-oxo-MEHP) is a secondary metabolite produced by cytochrome P450 enzyme-mediated oxidation of di(2-ethylhexyl) phthalate. Exposure levels of Mono (2-ethyl-5-oxohexyl) phthalate are associated with late-onset hypogonadism. Mono (2-ethyl-5-oxohexyl) phthalate can be used for research on mechanisms related to male reproductive endocrine disorders .
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Cat. No.: HY-137547
CAS No.: 57930-92-4
Research Areas:  

Metabolic Disease

20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.
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Cat. No.: HY-182421
CAS No.: 925924-27-2
Target:  

Kisspeptin Receptor

Research Areas:  

Endocrinology Cancer

GPR54 antagonist‑1 is a GPR54 antagonist with IC50 values of 3.6 nM and 15 nM against human and rat GPR54, respectively. GPR54 antagonist‑1 shows blood‑brain barrier penetration. GPR54 antagonist‑1 blocks the function of human and rat GPR54 receptors. GPR54 antagonist‑1 suppresses plasma luteinizing hormone levels in castrated male rats. GPR54 antagonist‑1 can be used for the study of prostate cancer and endometriosis .
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Cat. No.: HY-32351BR
CAS No.: 73809-05-9
Synonyms: 3-epi-25-hydroxy Cholecalciferol (Standard)
Research Areas:  

Endocrinology

3-epi-Calcifediol (Standard) is the analytical standard of 3-epi-Calcifediol. This product is intended for research and analytical applications. 3-epi-25-hydroxy Vitamin D3 is the C-3 epimer of 25-hydroxy vitamin D3.1 Dietary administration of 3-epi-25-hydroxy vitamin D3 (0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, weanling rats.
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Cat. No.: HY-B1986R
CAS No.: 72-55-9
Synonyms: 4,4'-DDE (Standard); p,p'-Dichlorodiphenyldichloroethylene (Standard)
p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women .
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Cat. No.: HY-B2007R
CAS No.: 79241-46-6
Fluazifop-P-butyl (Standard) is the analytical standard of Fluazifop-P-butyl (HY-B2007). This product is intended for research and analytical applications. Fluazifop-P-butyl is an orally active herbicide and ACCase inhibitor. Fluazifop-P-butyl blocks the formation of malonyl-CoA, disrupts lipid synthesis in sensitive plants, and exhibits concentration-dependent phytotoxicity to non-target maize seedlings. Fluazifop-P-butyl induces oxidative stress in male Wistar rats, impairs their liver and kidney functions, and disrupts testicular function .
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Cat. No.: HY-P2446
CAS No.: 83539-08-6
Synonyms: APTAA-LHRH
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

ORG 30276 (APTAA-LHRH) is a potent GnRH antagonist that effectively reduces serum LH and FSH levels in male rats. ORG 30276 significantly decreases unoccupied pituitary GnRH receptors, leading to suppressed gonadotropin secretion. ORG 30276 treatment results in a considerable reduction in mRNA levels of gonadotropin beta-subunits in the pituitary gland. ORG 30276's effects on gonadotropin dynamics can be selectively reversed by the replacement of specific sex steroids, with androgens being particularly effective for the FSH beta-subunit mRNA levels.
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Cat. No.: HY-W019824
CAS No.: 762-29-8
Farnesylacetone acts as a transcriptional regulator, RNA synthesis modulator, and male hormone. Farnesylacetone can be extracted from the androgenic glands of the green crab (Carcinus maenas). Farnesylacetone modulates transcriptional processes, inhibits uridine incorporation into all types of RNA and leucine incorporation into ovaries, while stimulating uridine incorporation into tRNA/poly (A) + RNA and leucine incorporation into testes. It suppresses electron transport in mitochondrial Complex I and Complex II. Farnesylacetone inhibits vitellogenesis in crustacean ovaries and stimulates uridine incorporation in crustacean intestines. It functions as an androgen in crustaceans .
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Cat. No.: HY-W197533
CAS No.: 65474-79-5
3-Hydroxymethyl-β-carboline is a Benzodiazepine antagonist with a Ki value of ~1470 nM. 3-Hydroxymethyl-β-carboline reverses Flurazepam-induced sleep, cerebrovascular and cerebral metabolic inhibition, and also partially reverses Flurazepam-induced decreases in blood pressure and heart rate. 3-Hydroxymethyl-β-carboline disrupts the anticonvulsant and anxiolytic effects of Diazepam in male mice. 3-Hydroxymethyl-β-carboline has no effect on sodium-dependent high-affinity choline uptake in rat cortical or hippocampal synaptosomes .
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Cat. No.: HY-137967
CAS No.: 38482-81-4
Purity:  ≥98.0%
Synonyms: Genistein 7-O-glucuronide
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Genistein 7-β-D-Glucuronide (Genistein 7-O-glucuronide) is the primary phase II metabolite of Genistein (HY-14596) in human and rat hepatocytes. Genistein 7-β-D-Glucuronide undergoes distinct deconjugation in different functional assays. Genistein 7-β-D-Glucuronide is produced via hepatic microsomal glucuronidation and shows a mild age-related increase in intrinsic clearance in male F344 rats. Genistein 7-β-D-Glucuronide can be used for research on metabolism .
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Cat. No.: HY-B2015S
CAS No.: 1189903-75-0
Carbosulfan-d18 is the deuterium labeled Carbosulfan. Carbosulfan is an orally active AChE inhibitor that hydrolyzes to Carbofuran in organisms to exert insecticidal effects. Carbosulfan exhibits broad-spectrum insecticidal activity, and it also induces severe oxidative stress by enhancing lipid peroxidation and impairing the antioxidant defense system. Carbosulfan causes reproductive toxicity in male rats and developmental disorders in their offspring. Carbosulfan shows persistence in paddy field environments and potential hazards to non-target organisms, and it is commonly used in studies related to reproductive toxicity and environmental risk assessment .
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Cat. No.: HY-N19639
CAS No.: 141364-77-4
Tyromycin A is an inhibitor targeting Leu-AP, Cys-AP and CP-A, with an IC50 value of 25-41 μg/mL against porcine Leu-AP and an IC50 value of 60 μg/mL against bovine CP-A. Tyromycin A inhibits the hydrolytic activity of target peptidases and exhibits selective activity against Gram-positive bacteria. Tyromycin A moderately inhibits the infectivity of HCV in human hepatocytes, with an IC50 of 6.6 μM, and its inhibitory activity depends on the two maleic anhydride domains. Tyromycin A can be used in studies related to Gram-positive bacterial infections and hepatitis C virus infections .
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Cat. No.: HY-P12119
Research Areas:  

Neurological Disease

RTI-263 is a biased Neuropeptide S receptor agonist. RTI-263 produces anxiolytic-like effects in rodents. RTI-263 reduces cocaine-seeking behavior in both male and female rats. RTI-263 does not modulate behaviors associated with natural rewards, including palatable food intake and fasting-induced food intake in rats. RTI-263 enhances memory in rodents without inducing increased arousal. RTI-263 can be used in studies related to substance use disorders and cocaine addiction .
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Cat. No.: HY-W011215R
CAS No.: 84-75-3
Dihexyl phthalate (Standard) is the analytical standard of Dihexyl phthalate (HY-W011215). This product is intended for research and analytical applications. Dihexyl phthalate is an orally active phthalate ester (PAEs) widely used as a plasticizer, and it acts as an environmental endocrine disruptor. Dihexyl phthalate exhibits endocrine-disrupting and reproductive toxic properties, induces oxidative stress and inflammation, and ultimately causes apoptosis and damage to reproductive organs such as the testes. Dihexyl phthalate can be used in studies related to developmental toxicity, embryonic lethality, teratogenicity, and abnormal development of the male reproductive system .
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Cat. No.: HY-W040074
CAS No.: 23273-91-8
Synonyms: Diglycine hydrochloride hydrate; Gly-Gly (HCl H2O)
Glycylglycine hydrochloride hydrate is a non-selective Glycylglycine hydrochloride hydrate dipeptidase substrate and iNOS inhibitor. Glycylglycine hydrochloride hydrate can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine hydrochloride hydrate promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine hydrochloride hydrate can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis) .
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Cat. No.: HY-W677042
CAS No.: 1153-51-1
Synonyms: 5α-Androst-16-en-3α-ol
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

α-Androstenol (5α-Androst-16-en-3α-ol) is a steroid pheromone that has been found in boar testes and male axillary sweat. α-Androstenol is also a positive allosteric modulator of GABAA receptors, which enhances GABA-activated currents in primary mouse cerebellar granule cells (EC50 of 0.4 μM). α-Androstenol produces anxiolytic-like, antidepressant-like, and anticonvulsant effects in mice. α-Androstenol can be used for the research of seizures .
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Cat. No.: HY-W747104
CAS No.: 52957-16-1
Target:  

Sex Pheromone

(9E)-Tetradecen-1-ol is a pheromone that has no significant sexual attraction when used alone and can be secreted from the abdomen of the female Bertha armyworm moth (Mamestra configurata (Walker)). Isolate in tip extract to get in isolate. Another pheromone (Z)-11-hexadecen-1-ol was also isolated at the same time. Only when the two pheromones are mixed do they show male attraction (the ratio of C16:C14 in the mixture is about 19:1). optimal) .
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Cat. No.: HY-106591A
CAS No.: 106-87-6
Purity:  ≥98.0%
Synonyms: Vinylcyclohexene diepoxide
4-Vinylcyclohexene dioxide (4-Vinylcyclohexene diepoxide) is an orally active metabolite of 4-vinylcyclohexene. 4-Vinylcyclohexene dioxide induces Apoptosis, increases intracellular ROS, and activates the PI3K/Akt/mTOR pathway. 4-Vinylcyclohexene dioxide selectively damages small ovarian follicles, inhibits granulosa cell function, and disrupts the male reproductive system. 4-Vinylcyclohexene dioxide can be used in the study of premature ovarian insufficiency, reproductive toxicity, and related fertility disorders .
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