285 Results for "

Angiotensin-converting Enzyme (ACE)

" in MedChemExpress (MCE) Product Catalog:
Products (285)

285 Results for "Angiotensin-converting Enzyme (ACE)" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N5063
CAS No.: 147331-98-4
Plantainoside D, a phenylethanoid glycosides, is a IKK-β inhibitor with diverse biological activities. Plantainoside D shows inhibitory activity of angiotensin-converting enzyme (ACE) with an IC50 of 2.17 mM. Plantainoside D significantly reduces the release of glutamate from nerve terminals in the cerebral cortex of rats by inhibiting the voltage-dependent calcium channel (VDCCs) and protein kinase C (PKC) signaling cascade. Plantainoside D significantly alleviates cell apoptosis by inhibiting the generation of ROS and the activation of NF-κB. Plantainoside D significantly improves acute lung injury (ALI) induced by sepsis by regulating the Sirt3/NLRP3 signaling pathway. Plantainoside D can be used for the study of neuroprotection, antioxidant, anti-inflammation, antihypertension .
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2
2 Cited Publications
Cat. No.: HY-15275
CAS No.: 582315-72-8
Purity:  99.59%
BMS-265246 is a potent and selective cyclin-dependent kinase CDK1 and CDK2 inhibitor, with IC50 values of 6 and 9 nM, respectively. BMS-265246 inhibits CHI3L1 (chitinase 3-like-1) stimulation of ACE2 (angiotensin converting enzyme 2) and SPP (viral spike protein priming proteases). BMS-265246 can be used for ovarian cancer and COVID-19 research .
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2
2 Cited Publications
Cat. No.: HY-122949
CAS No.: 91590-76-0
Purity:  ≥97.0%
Momordicine I is a cucurbitane-type triterpenoids. Momordicine I suppresses glioma growth by promoting apoptosis and impairing mitochondrial oxidative phosphorylation. Momordicine I inhibits glycolysis, lipid metabolism, induces autophagy in HNC cells to suppress head and neck cancer growth. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ. Momordicine I exerts its cardiovascular benefits by upregulating nitric oxide, inhibiting the activity of angiotensin-converting enzyme (ACE), activating the PI3K/Akt pathway, reducing oxidative stress and inflammation. Momordicine I inhibits AKT1, IL-6, and SRC, suggesting its potential application in type 2 diabetes .
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1
1 Cited Publications
Cat. No.: HY-100450
CAS No.: 78606-80-1
Purity:  ≥98.0%
BML-111, a lipoxin A4 analog, is a lipoxin A4 receptor agonist. BML-111 represses the activity of angiotensin converting enzyme (ACE) and increases the activity of angiotensinconverting enzyme 2 (ACE2). BML-111 has antiangiogenic, antitumor and anti-inflammatory properties .
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1
1 Cited Publications
Cat. No.: HY-114424A
CAS No.: 1208862-61-6
Purity:  98.48%
H-Ile-Pro-Pro-OH hydrochloride, a milk-derived peptide , inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM . Antihypertensive tripeptides .
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1
1 Cited Publications
Cat. No.: HY-A0043A
CAS No.: 92077-78-6
Synonyms: Ro 31-2848 monohydrate
Cilazapril monohydrate is an orally active prodrug of the angiotensin-converting enzyme (ACE) inhibitor Cilazaprilat (HY-A0113). Cilazapril monohydrate reduces plasma ACE activity. Cilazapril monohydrate can be used in the research of hypertension (including essential and renal hypertension) and congestive heart failure .
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1
1 Cited Publications
Cat. No.: HY-P7442
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACE2; Angiotensin I converting Enzyme 2; Angiotensin converting Enzyme 2; Angiotensin-converting Enzyme 2; ACEH; ACE-Related Carboxypeptidase; Angiotensin I converting Enzyme (Peptidyl-Dipeptidase A) 2; Metalloprotease MPROT15; Angiotensin-converting Enzy
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7443
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACE2; Angiotensin I converting Enzyme 2; Angiotensin converting Enzyme 2; Angiotensin-converting Enzyme 2; ACEH; ACE-Related Carboxypeptidase; Angiotensin I converting Enzyme (Peptidyl-Dipeptidase A) 2; Metalloprotease MPROT15; Angiotensin-converting Enzy
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-U00041
CAS No.: 81045-50-3
Synonyms: Pivopril; RHC 3659(S)
Pivalopril is a new orally active angiotensin converting enzyme (ACE) inhibitor.
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1
1 Cited Publications
Cat. No.: HY-B0655
CAS No.: 81938-43-4
Synonyms: SQ26991
Zofenopril Calcium (SQ26991) is an orally active angiotensin-converting enzyme (ACE) inhibitor with antioxidant activity and cardioprotective effects. Zofenopril Calcium reduces ROS production and GSH consumption and helps inhibit foam cell formation, thus slowing the progression of atherosclerosis. Zofenopril Calcium prevents cardiac damage caused by chronic Doxorubicin (HY-15142A) .
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1
1 Cited Publications
Cat. No.: HY-14393R
CAS No.: 518-82-1
Synonyms: Frangula emodin (Standard)
Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .
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1
1 Cited Publications
Cat. No.: HY-N5139
CAS No.: 93685-90-6
Synonyms: Lecithins, egg yolk; Belovo PL 85
Lecithins, egg (Lecithins, egg yolk; Belovo PL 85) is an orally active natural phospholipid mixture extracted from egg yolks . Lecithins, egg inhibits the activities of acetylcholinesterase (AChE) and angiotensin-converting enzyme (ACE). Lecithins, egg exhibits antibacterial, antioxidant and anti-inflammatory activities, and helps delay cellular senescence. Lecithins, egg enhances nerve conduction, improves memory and cognitive function, and exerts positive effects on delaying neurodegenerative diseases. Lecithins, egg promotes lipid absorption and alleviates diarrhea. Lecithins, egg acts as a high-efficiency drug carrier for the preparation of targeted drug delivery systems such as liposomes .
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Cat. No.: HY-B0378A
CAS No.: 82586-52-5
Synonyms: RS-10085
Moexipril hydrochloride (RS-10085) is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). Moexipril hydrochloride exhibits antihypertensive and neuroprotective effects - .
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Cat. No.: HY-105858
CAS No.: 13589-06-5
Purity:  98.03%
Synonyms: Ile-Trp
H-Ile-Trp-OH (Ile-Trp), a dipeptide, is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 0.7 μM. H-Ile-Trp-OH inhibits predominantly the C-domain of ACE .
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Cat. No.: HY-B1433
CAS No.: 95153-31-4
Synonyms: S 9780
Perindoprilat (S 9780) is an angiotensin-converting enzyme (ACE) inhibitor with the IC50 value ranging from 1.5 to 3.2 nM. Perindoprilat can be used in hypertension research .
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Cat. No.: HY-125112
CAS No.: 35927-38-9
Purity:  95.92%
Vicenin 1 is a C-glycosylflavone that has an inhibitory effect on angiotensin-converting enzyme (ACE)(IC50=52.50 μM) .
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Cat. No.: HY-107337
CAS No.: 83435-67-0
Purity:  ≥98.0%
Delapril hydrochloride is an angiotensin-converting enzyme (ACE) inhibitor for the treatment of cardiovascular diseases .
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Cat. No.: HY-B0279S
CAS No.: 1132661-86-9
Synonyms: HOE-498-d5
Ramipril-d5 is the deuterium labeled Ramipril. Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.
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Cat. No.: HY-A0116A
CAS No.: 951393-55-8
Synonyms: Trandolaprilat hydrate; RU 44403 hydrate
Trandolaprilate hydrate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate hydrate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity .
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Cat. No.: HY-108321
CAS No.: 81872-10-8
Zofenopril is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 81 μM.
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