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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
534 Results for "
MCF7 cells
" in MedChemExpress (MCE) Product Catalog:
Products (534)
534 Results for "MCF7 cells" in MCE Product Catalog:
1
1 Cited Publications
Research Areas:
PROTAC HSP90 degrader BP3 is a potent and selective degradation of HSP90 in a CRBN-dependent fashion. PROTAC HSP90 degrader BP3 has a certain degradation effect on HSP90 protein in MCF-7 cells (DC50=0.99 μM). PROTAC HSP90 degrader BP3 inhibits the growth of breast cancer cell . PROTAC HSP90 degrader BP3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
1
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MS4322 (YS43-22) is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5. MS4322 can be used for the research of breast cancer, lung cancer, and hepatocellular cancer. (Pink: PRMT5 ligand (HY-173092); Blue: E3 ligase ligand HY-112078); Black: linker (HY-124780); E3+linker (HY-173093 )) .
1
1 Cited Publications
Cat. No.: HY-N7012
CAS No.: 29080-58-8
Synonyms: 5-Hydroxy-3',4',7-trimethoxyflavone
1
1 Cited Publications
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σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist (pKi=10.28). σ1 Receptor antagonist-1 inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells .
Cat. No.: HY-W016794
CAS No.: 3565-26-2
Research Areas:
NSC3852 exhibits anti-proliferative activity against cancer cell MCF-7. NSC3852 promotes the ROS generation, DNA damage, and apoptosis in MCF-7. NSC3852 exhibits anti-tumor against leukemia in mouse model
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Benzyl DC-81 (Compound 6a) is an anticancer agent with antiproliferative activity against A375 and MCF-7 cells .
Cat. No.: HY-137099A
Purity: ≥99.0%
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Genistein 7-sulfate sodium is a metabolite of genistein that can reduce the activity of estrogen agonists in MCF-7 cells. Genistein 7-sulfate sodium can promote the growth of MCF-7 cells at concentrations of 10 μM and above .
Cat. No.: HY-N2887
CAS No.: 1354638-93-9
Category:
Natural Products Aralia cordata Thunb. Plants Disease Research Fields Cancer Araliaceae Extract
Target:
Cat. No.: HY-N6990
CAS No.: 29388-33-8
Category:
Lignans Phenols Polyphenols Phenylpropanoids Plants Other Families Extract Disease Research Fields Cancer
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Cat. No.: HY-N4010
CAS No.: 52591-10-3
Category:
Phenols Polyphenols Iridaceae Extract Plants Thymelaeaceae Extract Belamcanda chinensis (Linn.) Redouté Disease Research Fields Aquilaria sinensis (Lour.) Spreng. Cancer
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Target:
Cat. No.: HY-137099
CAS No.: 182322-62-9
Target:
Research Areas:
Genistein 7-sulfate is a metabolite of genistein that can reduce the activity of estrogen agonists in MCF-7 cells. Genistein 7-sulfate can promote the growth of MCF-7 cells at concentrations of 10 μM and above .
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(S)-ErSO is the dextrorotatory enantiomer of ErSO. (S)-ErSO is inactive in MCF-7 cells (from patent WO2020009958A1, compound (s)-105) .
Cat. No.: HY-N8679
CAS No.: 27503-33-9
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Cat. No.: HY-N10846
CAS No.: 117456-86-7
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Cat. No.: HY-160811
CAS No.: 46739-60-0
hVEGF-IN-3 (compound 9) is a potent hVEGF inhibitor. hVEGF-IN-3 inhibits HT-29, MCF-7, and HEK-293 cells proliferation with IC50s of 61, 142, and 114 μM .
Cat. No.: HY-N5103
CAS No.: 36190-98-4
Category:
Flavonoids Monophenols Ammopiptanthus nanus (M. Pop.) Cheng f. Phenols Leguminosae Extract Plants Disease Research Fields Endocrinology Isoflavones
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Cat. No.: HY-103452
CAS No.: 151555-47-4
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RU58668 is a steroidal antiestrogen that can be used as a potent antiproliferative agent on MCF-7 cells. RU58668 has the potential for the breast cancer research .
Cat. No.: HY-W747516
CAS No.: 352304-41-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
