219 Results for "

active ingredient

" in MedChemExpress (MCE) Product Catalog:
Products (219)

219 Results for "active ingredient" in MCE Product Catalog:

2
Gambogenic acid
Gambogenic acid
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2 Cited Publications
Cat. No.: HY-N5024
CAS No.: 173932-75-7
Category:  

Ketones, Aldehydes, Acids Guttiferae Phenols Polyphenols Plants Garcinia hanburyi Hook. f. Disease Research Fields Cancer

Target:  

Histone Methyltransferase

Gambogenic acid is an active ingredient that can be isolated from gamboge. Gambogenic acid acts as an effective inhibitor of EZH2, specifically and covalently binds to Cys668 within the EZH2-SET domain, and induces EZH2 ubiquitination. Gambogenic acid can be used for the research of cancer .
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Recombinant Proteinase K (DNase & RNase free, animal free)
Recombinant Proteinase K (DNase & RNase free, animal free)
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2 Cited Publications
Cat. No.: HY-108717A
CAS No.: 39450-01-6
Synonyms: Recombinant Protease K (DNase & RNase free, animal free)
Target:  

Ser/Thr Protease

Research Areas:  

Others

Recombinant Proteinase K (Protease K) (DNase & RNase free, animal free) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K (DNase & RNase free, animal free) is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures. Proteinase K (DNase & RNase free, animal free) can be use for promoting methods of viral nucleic acid extraction, and detection. This product is of molecular biology grade, free of animal-derived ingredients, and is recombinantly purified from yeast .
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Neoline
Neoline
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1 Cited Publications
Cat. No.: HY-N0478
CAS No.: 466-26-2
Synonyms: Bullatine B
Category:  

Alkaloids Piperidine Alkaloids other families Plants

Target:  

Others

Neoline (Bullatine B) is the active ingredient of the active ingredient (PA), which can be used to cure the disease. Neoline Flow Suppression Nav1.7 Electrical Flow Control (VGSC), improve diabetes mechanical pain sensitivity. Neoline has a list of compounds that can be used, research on its use, and the quality of its processing during processing in pain .
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Racanisodamine
Racanisodamine
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1 Cited Publications
Cat. No.: HY-N2064
CAS No.: 17659-49-3
Category:  

Alkaloids Other Alkaloids Anisodus tanguticus (Maxinowicz) Pascher Plants Solanaceae

Target:  

mAChR

Racanisodamine is an orally active, non-selective Muscarinic Acetylcholine Receptor (mAChR) antagonist. Racanisodamine is a racemate of Anisodamine, and the two share similar pharmacological effects. Racanisodamine is an active ingredient of eye drops for myopia control. Racanisodamine can be used in research on myopia and late dumping syndrome .
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Cucurbitacin D
Cucurbitacin D
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1 Cited Publications
Cat. No.: HY-N1986
CAS No.: 3877-86-9
Category:  

Triterpenes Terpenoids Cucurbitaceae Trichosanthes kirilowii Maxim. Plants Disease Research Fields Cancer

Target:  

HSP Apoptosis

Cucurbitacin D is the active ingredient in Trichosanthes kirilowii and can disrupt the interaction between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D is an inflammasome activator. Cucurbitacin D induces cell cycle arrest and cell apoptosis, exhibiting anti-tumor and anti-inflammatory effects .
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Carvacrol (Standard)
Carvacrol (Standard)
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1 Cited Publications
Cat. No.: HY-N0711R
CAS No.: 499-75-2
Synonyms: Cymophenol (Standard)
Category:  

Monophenols Labiatae Phenols Plants Derris elliptica (Roxb.) Benth.

Target:  

Reference Standards Notch Apoptosis Fungal Endogenous Metabolite Bacterial

Carvacrol (Standard) is the analytical standard of Carvacrol. This product is intended for research and analytical applications. Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .
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Omalizumab
Omalizumab
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1 Cited Publications
Cat. No.: HY-P9950
CAS No.: 242138-07-4
Synonyms: Olizumab; rhuMab-E25; IGE25; RG-3648

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a KD of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a KD of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research . The component ratio of this product is Active ingredient : Excipients = 1:1.3-1:1.5.
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Ziyuglycoside I
Ziyuglycoside I
0 Images
1 Cited Publications
Cat. No.: HY-N0331
CAS No.: 35286-58-9
Category:  

Triterpenes Sanguisorba officinalis Linn. Terpenoids Rosaceae Plants Disease Research Fields Cancer

Target:  

MDM-2/p53 Apoptosis

Ziyuglycoside I isolated from S. officinalis root, has anti-wrinkle activity, and increases the expression of type I collagen. Ziyuglycoside I could be used as an active ingredient for cosmetics . Ziyuglycoside I triggers cell cycle arrest and apoptosis mediated by p53, it can be a potential agent candidate for treating triple-negative breast cancer (TNBC) .
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1
Allyl methyl sulfide
Allyl methyl sulfide
0 Images
1 Cited Publications
Cat. No.: HY-128447
CAS No.: 10152-76-8
Purity:  ≥98.0%
Category:  

Infection Natural Products Liliaceae Plants Endogenous metabolite Disease Research Fields  A．Sativam L. var．Viviparum Regel

Target:  

Endogenous Metabolite SOD NF-κB GLUT

Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications .
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1,3-Dihydroxyacetone
1,3-Dihydroxyacetone
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1 Cited Publications
Cat. No.: HY-Y0335
CAS No.: 96-26-4
Synonyms: Dihydroxyacetone
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Bacterial Antibiotic Drug Intermediate

1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227) .
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1,3,6-Tri-O-galloyl-beta-D-glucose
1,3,6-Tri-O-galloyl-beta-D-glucose
0 Images
1 Cited Publications
Cat. No.: HY-N6006
CAS No.: 18483-17-5
Synonyms: 1,3,6-Tri-O-galloyl-β-D-glucose
Category:  

other families Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Others

1,3,6-Tri-O-galloyl-beta-D-glucose is a non-covalent inhibitor of tyrosinase (TYR), which can block the rate-limiting step of melanin synthesis and inhibit melanin deposition. 1,3,6-Tri-O-galloyl-beta-D-glucose has antioxidant and anti-inflammatory activities and can be used as a natural active ingredient to develop anti-freckle and whitening skin care products .
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(rel)-ML-SI3
(rel)-ML-SI3
0 Images
1 Cited Publications
Cat. No.: HY-139426A
CAS No.: 2108567-79-7
Purity:  99.81%
Synonyms: trans-ML-SI3
Target:  

TRP Channel Autophagy

Research Areas:  

Cancer

(rel)-ML-SI3 is one of the active ingredients of ML-SI3 (HY-139426) (another component is (cis)-ML-SI3) that targets three isoforms of TRPML. (rel)-ML-SI3 is an inhibitor of TRPML1 and TRPML3 (IC50=3.1 μM/28.5 μM), and a potent activator of TRPML2 (EC50=3.3 μM) .
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Withanone
Withanone
0 Images
1 Cited Publications
Cat. No.: HY-129692
CAS No.: 27570-38-3
Purity:  93.06%
Category:  

Withania somnifera Plants Solanaceae Steroids

Target:  

iGluR

Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .
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Lariciresinol
Lariciresinol
0 Images
1 Cited Publications
Cat. No.: HY-N3405
CAS No.: 27003-73-2
Category:  

Human Gut Microbiota Metabolites Lignans Arabidopsis thaliana Phenylpropanoids Plants Brassicaceae Endogenous metabolite

Target:  

Glycosidase Bcl-2 Family Apoptosis TGF-β Receptor NF-κB Fungal

Lariciresinol is an orally active ingredient. Lariciresinol can be isolated from Arabidopsis thaliana. Lariciresinol inhibits α-glucosidase activity (IC50 of 6.97 μM; Ki of 0.046 μM). Lariciresinol dereases Bcl-2, upregulates Bax and induces Apoptosis. Lariciresinol regulates TGF-β and NF-κB pathways. Lariciresinol has antitumor activity against liver cancer, gastric cancer, and breast cancer. Lariciresinol shows antifungal activity and anti-diabetic activity .
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4-Hydroxyderricin
4-Hydroxyderricin
0 Images
1 Cited Publications
Cat. No.: HY-N7204
CAS No.: 55912-03-3
Category:  

Flavonoids Chalcones Monophenols Phenols Plants Umbelliferae Ondetia linearis Benth.

Target:  

Monoamine Oxidase Dopamine β-hydroxylase Apoptosis

4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation . 4-Hydroxyderricin is promising for research of inflammatory diseases .
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Astragaloside I
Astragaloside I
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Cat. No.: HY-N0432
CAS No.: 84680-75-1
Synonyms: Astrasieversianin IV; Cyclosieversioside B
Category:  

Triterpenes other families Leguminosae Terpenoids Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Metabolic Disease Plants Disease Research Fields

Target:  

Wnt β-catenin

Astragaloside I, one of the main active ingredients in Astragalus membranaceus, has osteogenic properties. Astragaloside I stimulates osteoblast differentiation through activating the Wnt/β-catenin signaling pathway .
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1-Cyclohexanol
1-Cyclohexanol
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Cat. No.: HY-Y1217
CAS No.: 108-93-0
Synonyms: Hydroxycyclohexane; NSC 54711; Naxol; Cyclohexanol
1-Cyclohexanol (Hydroxycyclohexane; NSC 5471) is an orally active Cramer Class I flavor ingredient that can be used in fragrances. 1-Cyclohexanol has a wide margin of safety and is environmentally friendly .
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Theogallin
Theogallin
0 Images
Cat. No.: HY-122924
CAS No.: 17365-11-6
Purity:  99.93%
Synonyms: 3-Galloylquinic acid
Category:  

Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Theaceae

Target:  

Others

Theogallin (3-Galloylquinic acid) is an active ingredient in decaffeinated green tea extract. Theogallin has antidepressive and cognition enhancing effect .
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Ethyl cinnamate
Ethyl cinnamate
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Cat. No.: HY-Y0121
CAS No.: 103-36-6
Category:  

Kaempferia galanga L. Other Diseases Other Phenylpropanoids Phenylpropanoids Plants Disease Research Fields Zingiberaceae

Target:  

Environmental Pollutants Apoptosis Parasite VEGFR

Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
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Methyl nicotinate
Methyl nicotinate
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Cat. No.: HY-B1695
CAS No.: 93-60-7
Synonyms: Nicotinic acid methyl ester
Category:  

Natural Products Microorganisms Disease Research Fields Inflammation/Immunology

Target:  

Others

Methyl nicotinate (Nicotinic acid methyl ester) is an orally active vasodilator. Methyl nicotinate has analgesic activity. Methyl nicotinate causes local skin erythema when applied topically to the skin. Methyl nicotinate is used as an active ingredient in over-the-counter topical preparations for the study of muscle and joint pain .
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