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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1899 Results for "
coenzyme
" in MedChemExpress (MCE) Product Catalog:
Products (1899)
1899 Results for "coenzyme" in MCE Product Catalog:
10
10 Cited Publications
Cat. No.: HY-N0303
CAS No.: 58186-27-9
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Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM) . Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells . Idebenone quickly crosses the blood-brain barrier.
7
7 Cited Publications
Synonyms: Acetyl-CoA trisodium
7
7 Cited Publications
Synonyms: Acetyl-CoA lithium
7
Category:
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7
7 Cited Publications
Synonyms: Sodium pantothenate; Vitamin B5 sodium
Category:
Alkaloids Other Alkaloids Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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7
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SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM . SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR) .
7
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
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7
7 Cited Publications
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7
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NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .
7
Category:
Microorganisms Animals Ketones, Aldehydes, Acids Other Diseases Plants Other Families Extract Disease Research Fields
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6
6 Cited Publications
6
6 Cited Publications
5
5 Cited Publications
Synonyms: Succinyl-CoA sodium
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
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5
5 Cited Publications
Cat. No.: HY-W011727
CAS No.: 853645-22-4
Synonyms: Pyridoxal phosphate hydrate
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5
5 Cited Publications
Cat. No.: HY-W011727A
CAS No.: 41468-25-1
Synonyms: Pyridoxal phosphate monohydrate
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4
4
4 Cited Publications
Cat. No.: HY-N4193
CAS No.: 59870-65-4
Category:
Cardiovascular Disease Flavonoids Flavonones Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields Glycyrrhiza uralensis Fisch.
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4
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Nevanimibe (PD-132301) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe induces cell apoptosis and has the potential for adrenocortical cancer .
4
4 Cited Publications
Synonyms: PD-132301 hydrochloride; ATR101 hydrochloride
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Research Areas:
Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
